Under pulse exchangeability within blocks, testing did not detect late SEEG response change across ten pulses in five patients
This study tested late SEEG response change across ten repeated stimulation pulses. It used public OpenNeuro ds004457 version 1.0.2 data from five patients. The fixed set contained 436 block-contact links, 123 blocks, and 19 ventral temporal receiving contacts. A separate middle pulse group formed each response template. The score compared late and early groups in the 100 to 500 ms window, with a matched before-window control. The mean of five patient medians was +0.0580 before-window pulse variation units. The descriptive patient interval was [-0.0003, +0.1200]. The planned two-sided pulse order test gave p = 0.2048 from 9999 draws. The test did not detect change at the 0.05 level. It assumes joint pulse exchangeability within blocks and concerns this fixed cohort. It does not prove constant responses or a neural cause. The estimated direction changed with template and offset choices. All planned checks are reported. Fresh retrieval of 57 pinned raw files rebuilt every archived array exactly. Independent waveform calculations and repeat runs checked the results. The package preserves code, pulse data, source records, random orders, proof notes, figures, and repeat instructions.
stereoelectroencephalography · electrical stimulation · pulse order · response change · exchangeability · waveform template
References
5- usesExpected eight-pulse late ventral temporal SEEG shape energy had a 55 percent mean patient median variance share in five patients sci:sha256:b85222fd5c14a01b1392374e9246f746272101232d8e238c4c58364473b5ec29
This study uses the saved pulse arrays, source metadata, raw file manifest, and retrieval and rebuild code. Fresh raw extraction checked these inputs before the new pulse order test.
- usesInterleaved pulse splits gave an uncertain mean patient median SEEG correlation gain of 0.008 in five patients sci:sha256:0157822b95095ada37d6604011da4e5ea8517b34e4de08c81710f23a426e1f67
This study retains the original contact rule and pulse bin extraction. The original extraction code is preserved for inspection. The earlier pulse split results were read before the new study plan.
- usesdoi:10.18112/openneuro.ds004457.v1.0.2
The analysis used OpenNeuro ds004457 version 1.0.2; the saved source records identify this exact version.
- doi:10.1101/2022.07.06.498994
- doi:10.1371/journal.pcbi.1011105
Cited by
4 publicationsPublic catalog entries on Sciscape.
- usesUnder pulse exchangeability within blocks, testing did not detect late posterior cingulate SEEG response change across ten hippocampal complex pulses in eight patients
This publication supplied the separate-template response score and the shared pulse-order rule. Its archived code supplied MEF read examples. We applied these methods to the HC to PCC circuit in ds004696.
- usesStudent t intervals covered 93.48% of bins but 45.93% of full SEEG waveforms in five patients
We read this pulse order report before the fixed plan. It informed the choice to preserve chronological pulse order. The present study tests interval coverage for a different selected receiver set.
- usesAn 80 percent band gave 82.1 percent mean coverage of test SEEG pulse waveforms in five patients at 50 to 250 ms
Provided context, read after the primary calculation, on the exchangeability assumption in a different within-block response-change test. It did not change the current primary analysis or supply its numerical results.
- usesUnder joint pulse exchangeability within blocks, testing did not detect excess adjacent SEEG response similarity 100 to 500 ms after stimulation in five patients
This publication provides the binned pulse arrays, fixed source metadata, raw object manifest, and retrieval and rebuild code. The present study uses these inputs to test adjacent waveform similarity against a matched before-pulse control.