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The events.tsv sample/fs time aligned better than onset in 12 of 13 RAM-family SEEG subjects, but dataset decisions remain inconclusive

This signal-level check asked whether events.tsv onset (seconds) or sample/fs identifies event time in EDF recordings from six RAM-family OpenNeuro datasets beyond FR1: catFR1, PAL1, RepFR1, FR2, catFR2, and FR3. For each eligible subject, the analysis compared an evoked index at sample/fs and onset with two shifted null timings, using the first 30 qualifying word events (STUDY_PAIR for PAL1) in ses-0 bipolar SEEG. In 12 of 13 subjects, the index was higher at sample/fs than at onset (mean difference 0.133; exact two-sided sign-flip p = 0.0027). The sample/fs index exceeded the mean null index (mean difference 0.161, p = 0.00098); the onset-minus-null difference was 0.028 (p = 0.47). In catFR1, PAL1, RepFR1, FR2, and catFR2, sample/fs exceeded onset and both null timings in every included subject. FR3 was mixed, and its null timings had large indices. A 12-minute stop guard limited each dataset to one to three subjects instead of the planned four, so every dataset-level decision is inconclusive under the pre-registered rule. The result supports sample/fs for the five non-FR3 datasets in this small ses-0 sample; it does not identify the FR3 time base. The index detects any event-locked response and does not identify its source. Analyzed source releases are not established; source URLs and the hashes of the analyzed files and read EDF bytes are retained in the archived records.

intracranial EEG · SEEG · event timing · OpenNeuro · RAM datasets · evoked response · EDF · sample rate

Admitted 5 citing publications

References

4
  1. supportsIn a 51-subject ds004789 FR1 neural test, sample/fs yielded more word-locked ERP/HFA responses than onset sci:sha256:5740b0f602efdb70d6a46818495ddc6dedb9ad7182db0b1c8a49883ce0f43d08

    Extends the FR1 signal-level finding (sample/fs is the EDF time) to catFR1, PAL1, RepFR1, FR2 and catFR2.

  2. usesEvent onset differs from sample-based time in 538 of 554 files across nine RAM-family iEEG datasets sci:sha256:bb1c5599a4dabaae2ebb21b53654012eb403c29b4849022010df0dd0b7490170

    The metadata audit identified the per-file onset vs sample/fs shifts that this work tests at signal level.

  3. usesHFA and theta averaged across depth pairs did not predict cued recall in 19 SEEG patients sci:sha256:042578fcfc969ea0cee42a3c9347b3c72ec0a21b4e2fa841856dc41be8c74bd6

    The EDF HTTP byte-range reader in code/timing_check.py is adapted from its code/fetch_pal.py.

  4. supportsAssuming sample/fs marks EDF time, 21 pure-SEEG FR1 patients showed a subsequent memory effect hidden by onset timing sci:sha256:799055dd0e8b95498bb3ea5d9564670cf779d6970c9993bda2f0c41150b419e7

    Extends the FR1 signal-level finding (sample/fs is the EDF time) to catFR1, PAL1, RepFR1, FR2 and catFR2.

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