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A separate implementation reproduced the ten second calibration accuracy change across two seizures in 32 SEEG patients

A separate implementation reproduced ten second background calibration of a gamma power threshold in public stereoelectroencephalography (SEEG) data. The test used two seizures from each of 32 patients in OpenNeuro ds004100 version 1.1.3. Mean balanced accuracy was 69.53 percent with a fixed threshold and 69.38 percent after calibration. The change was -0.16 percentage points. The 95 percent patient bootstrap interval was -3.28 to +2.81 percentage points. This interval assumes independent patients with a common sampling distribution. It does not prove equal performance. A concurrent publication reported the same primary test. All 64 input hashes matched. All 1,280 primary decisions were identical, and all 32 patient results agreed within numerical tolerance. This is a computational reproduction on the same cohort. Five additional fixed settings also had intervals that included zero. The package adds a calibration utility and its proof for a pure additive change. It preserves source code, unchanged compact power data, full results, source range locks, raw examples, and repeat instructions. Fresh public retrieval checked all 757,770 source power values. An offline repeat reproduced all ten numerical output files exactly. The short excerpts do not measure continuous seizure detection or clinical benefit.

SEEG · epilepsy · seizure detection · gamma power · threshold calibration · balanced accuracy · reproducibility

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References

6
  1. A ten-second local baseline changed mean gamma threshold balanced accuracy by −0.16 percentage points in offline tests of 32 SEEG patients sci:sha256:4628cde38f261574ac92aeb8d0284355be797f071d5fdf9ed6b07717366a077b

    [Legacy relation: reproduces] A separate implementation reproduced the primary calibration test on the same 64 power files and 32 patients. All 1,280 decisions matched, and patient metrics agreed within numerical tolerance. This checks computation on shared inputs. It does not test a separate patient cohort.

  2. usesA gamma pair selected in one seizure gave mean AUC 0.779 in a separate seizure compared with 0.807 for pooled SEEG in 32 patients sci:sha256:c1866489dffd313ed6905dca81bba1130ad55ca68cc771f84d14d38f4839867c

    This archive supplied all 64 unchanged power files, dataset metadata, source version locks, extraction code, and raw examples. Its separate seizure results informed the calibration question.

  3. usesChoice among 12 scores gave a mean AUC gain of 0.011 in separate seizures from 29 ds004100 SEEG patients sci:sha256:33e4e621d074278abcce1fbf1ef462f526bdf5f640d2b9f2f743e687d17d9398

    Files and provenance from this earlier analysis are preserved in the direct source archive. They support the source chain and document reuse of the same public power data.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analysis uses the 64 power files derived from the HUP iEEG Epilepsy Dataset, exact version 1.1.3.

  5. doi:10.1007/s11517-016-1479-8
  6. doi:10.1016/j.clinph.2020.03.033

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