A gamma pair selected in one seizure gave mean AUC 0.779 in a separate seizure compared with 0.807 for pooled SEEG in 32 patients

We tested gamma pair selection with two seizures from each of 32 public SEEG patients in OpenNeuro ds004100 version 1.1.3. We selected the pair with the largest gamma rise in one seizure. Its mean AUC in the other seizure was 0.779, compared with 0.807 for mean pooling across matched pairs. The paired mean gain was -0.0275, with a 95 percent patient bootstrap interval of -0.0825 to 0.0222. The data did not establish a gain over pooling. Training AUC was 0.908 for the selected pair. All nine planned check intervals included zero. This test used short labeled windows and did not measure continuous seizure detection. The package preserves 64 power files, source records, code, window scores, exact sign counts, bootstrap samples, and reproduction instructions. Fresh source checks passed for all 64 recordings and 757,770 power values. The report also identifies a uniform-pair comparison added after the primary result.

stereoelectroencephalography · seizure · gamma power · AUC · signal selection · cross-seizure transfer · patient bootstrap