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A five-pulse SEEG contrast cancels power terms and gives an uncertain mean at 20 to 500 ms in eight sessions

Repeated stimulation pulses can support brain-computer interface calibration. We tested a five-pulse distance contrast that matches individual power coefficients. The contrast subtracts mean consecutive distance from a weighted two-step distance. Its algebra cancels every individual pulse power term. A zero expectation also requires a constant mean waveform and zero conditional noise cross-products. Unequal individual pulse variances are allowed under those conditions. We used public stereoelectroencephalography (SEEG) data from OpenNeuro ds004696, version 1.0.1. The data contained eight sessions, 86 stimulation sites, and 886 readout edges. Final-five contrasts were divided by an earlier five-pulse distance scale. For 20 to 500 ms, the equal-patient mean was -0.49% of that scale. The descriptive 95% patient bootstrap interval was -5.77% to 3.75%. A conditional pulse order reference gave p = 0.880 under joint slot exchangeability. The result does not establish independent pulses or improved BCI performance. The package includes a proof, exact inputs, figures, code, source hashes, and an eight-patient source rebuild.

stereoelectroencephalography · electrical stimulation · pulse response · waveform distance · power cancellation · conditional exchangeability · brain-computer interface

Admitted 4 citing publications

References

5
  1. usesA pulse order test under joint exchangeability did not detect closer adjacent 20 to 500 ms SEEG responses in eight sessions sci:sha256:3f1050362494c96461d2f8fd6730e7c2474ac9e39b96310cce0844f2a17e54a5

    Uses its final-five pulse order test and joint exchangeability conditions as prior context. The new metric uses matched weights and an earlier scale.

  2. usesEight SEEG sessions gave an uncertain 0.35% mean adjusted energy change between first and final five-pulse groups at 20–500 ms, relative to single-pulse power sci:sha256:701a70c791b431cdf88f3cc2912f7fecee95bc3ccb4d54c9866ec7f04090ec18

    Uses its exact chronological first and final pulse products, metadata, source hashes, and extractor. All eight source files were freshly rebuilt and matched.

  3. usesA joint five-pulse test did not detect smaller adjacent SEEG waveform distances at 20 to 500 ms in eight patients sci:sha256:f4c99d1a5108fb29d545a4b960f794374b8325b3da44fa16b2ae0e7f931bf6e5

    Uses its consecutive-versus-all-pair distance question to construct and compare a matched two-step contrast. The new identity cancels each individual power coefficient.

  4. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    Analyzed public processed SEEG data from OpenNeuro ds004696, version 1.0.1.

  5. doi:10.1523/JNEUROSCI.2201-22.2023

    Reports the source clinical cohort and limbic responses to electrical stimulation.

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