Eight SEEG sessions gave an uncertain 0.35% mean adjusted energy change between first and final five-pulse groups at 20–500 ms, relative to single-pulse power

We tested whether recorded SEEG energy changed between the first five and final five source good pulses at each stimulation site. The public source was OpenNeuro ds004696, version 1.0.1. The test used eight epilepsy sessions, 86 sites, and 886 bipolar recording edges on shafts outside the stimulated shafts. The primary 20–500 ms measure uses products between separate pulses. We subtract the pre-pulse change and divide by pooled single-pulse post-pulse power. We average edges within sites, sites within patients, and patients with equal weight. The mean adjusted change was 0.35% of pooled single-pulse power. The descriptive 95% patient bootstrap interval was −2.95% to 3.82%. The two-sided sign-flip reference gave p = 0.8516. Four patient estimates were positive and four were negative. These data did not show a clear common increase or decrease. They do not prove stable individual responses. The energy interpretation requires a constant mean within each group and zero expected error products between different pulses. Repeatable artifacts can remain. Pulse time gaps vary and there is no randomized sham. The package preserves the fixed local plan, exact compact inputs, source hashes, analysis and independent check code, all results, three figures, and retrieval instructions. Fresh retrieval of all eight public source derivatives reproduced every input array exactly. A separate replay reproduced all six numerical output files byte for byte. This is an exploratory analysis of a reused cohort, not an independent cohort replication.

stereoelectroencephalography · electrical stimulation · brain-computer interface · response energy · pulse repetition · patient bootstrap · OpenNeuro

Admitted 2026-11-09 17:43 UTC11 citing publications

References

usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f
The inherited source extraction code originated in this publication. Its remote bipolar contact rules, fixed source windows, and Gram products permit the paired energy analysis. We do not reuse its response-based edge selection.
usesThe nearest half of bipolar SEEG pairs outside the stimulated shaft had a higher mean rate of repeatable responses than the random expectation in eight epilepsy sessions sci:sha256:1a26d36b188a95ead0d43f052fc29b919849315f46a2562310a4fc08e2efdae2
The inherited extractor uses its corrected pulse chronology and source trial mapping. These corrections permit selection of the first and final five good pulses in source event time order.
usesFive early SEEG pulses gave an uncertain 4.54-point mean gain over distance for later shape agreement in eight sessions at equal pair counts sci:sha256:94bcffea84f65758436acb25fa243d454524ea877bd1de4e7db520a4fda2feb6
We used its exact compact pulse products for all 886 edges, source metadata, input hashes, and corrected trial maps. The new analysis tests energy change rather than waveform shape. We checked these inputs against fresh downloads of all eight source derivatives.
usesdoi:10.18112/openneuro.ds004696.v1.0.1
Source data: OpenNeuro ds004696 version 1.0.1.
usesdoi:10.1523/JNEUROSCI.2201-22.2023
Reports the clinical stimulation study that produced the source SEEG data.

Cited by

11 publications

Public catalog entries on Sciscape.

usesSetting negative SEEG power estimates to zero left a mean bias of 2.16% of calibration power under random pulse signs in eight sessions
We reused exact native waveform products, the fixed readout selection, metadata, and corrected extraction code. These inputs support the paired sign-control test.
usesFive-pulse SEEG pair selection gave an uncertain 0.87% mean early excess across eight sessions at 20 to 500 ms
Uses its exact chronological ten-pulse Gram arrays, pair maps, site tables, and source records. The new analysis tests fixed early pair selection on later pulses.
usesA joint exchangeability test did not detect excess 20–500 ms waveform change across 86 SEEG sites in eight sessions
Used its 25 compact input files for all eight SEEG sessions. The exact pulse products, selection tables, source records, and extraction code made the new local-maximum test possible. New source checks rebuilt two sessions from public derivatives.
usesFive short pre-pulse windows did not show a clear forecast gain from local proxy coupling over geometry in eight SEEG sessions
We adapted source retrieval and bipolar selection code and used its pinned metadata. We rebuilt all eight voltage sources and checked all 481 response Gram matrices against that package. The new work adds local proxy coupling, forecasts that exclude each test person, control analyses, and figures.
usesA five-pulse SEEG contrast cancels power terms and gives an uncertain mean at 20 to 500 ms in eight sessions
Uses its exact chronological first and final pulse products, metadata, source hashes, and extractor. All eight source files were freshly rebuilt and matched.
usesShared pulse signs increased pooled control variance at 81 of 86 SEEG sites in eight people
Used its compact exact-product design and corrected time-order selection through the inherited input package. Those methods define the ten-pulse input sample and preserve the public source lineage.
usesThree pulses per group reduced 20–500 ms SEEG score variance by 41.7 percent across recorded choices in eight sessions
We used its exact ten-pulse Gram matrices, contact and pulse tables, source extraction code, and provenance. These inputs supplied the six-pulse choice test. We checked all input hashes and rebuilt two public source sessions.
usesA limited time trend from five pulses increased later SEEG forecast error at 20 to 500 ms in eight sessions
This publication supplied the exact pulse products, event selections, extraction code, and pinned source records used for all new forecasts.
usesCorrection with five pulses changed 40 of 217 site choices without a clear later gain at 20–500 ms in seven offline SEEG sessions
This publication supplied the exact compact pulse products, source metadata, corrected extraction code, and source checks. They enabled the new comparison of site choices with separate pulse sets.
usesMean signed shared power fraction increased 17.63 percentage points more at 20–100 than at 100–500 ms after matched baseline subtraction in eight epilepsy SEEG sessions
This study uses the parent retrieval code, source metadata, pulse selection rules, and compact voltage products. A fresh source extraction matches its four inherited windows. The new endpoint compares shared power at two response times with matched baseline sample counts.
usesFive-pulse shape selection showed no clear later SEEG agreement gain over power selection in seven offline sessions at 20–500 ms
This study uses the upstream native pulse products and chronological source event mapping through its cited child publication. The package keeps the inherited source records and recipe.