The nearest half of bipolar SEEG pairs outside the stimulated shaft had a higher mean rate of repeatable responses than the random expectation in eight epilepsy sessions

We tested contact distance as a rule for the choice of bipolar SEEG recording pairs. This secondary analysis used OpenNeuro ds004696 version 1.0.1. It included 884 available pairs at 84 stimulation sites in eight patients with epilepsy. All recording pairs were outside the stimulated shaft. At each site, we selected the nearest half, with a ceiling for the pair count. A repeatable response had correlation of at least 0.8 between first-five and final-five pulse means in 20–500 ms. Sites had equal weight within each patient. Patients had equal weight. The nearest rule had a mean rate of 50.2 percent. The exact random expectation at the same count was 39.0 percent. The gain was 11.3 percentage points, with a 95 percent patient bootstrap interval of 3.7 to 19.5 points. Six patients had a gain, one had no change, and one had a loss. Five-pulse ranking gave a mean rate of 57.4 percent. The distance gain before the pulse was 0.04 points. Distance gave an incomplete initial selection rule in this sample. The outcome measures waveform shape within a session. It does not establish stable amplitude, long-term reliability, or clinical benefit. The package preserves code, exact trial products, native coordinates, all pair choices, four figures, source hashes, and reproduction instructions. One patient was rebuilt from the public source. All eight electrode tables were checked by fresh retrieval. The study uses data and code from a cited sci publication on the same cohort.

stereoelectroencephalography · electrical stimulation · bipolar recording · waveform repeatability · contact distance · brain-computer interface

Admitted 2026-11-09 15:41 UTC8 citing publications

References

usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f
We use the eight chronological trial-product archives, pair tables, source metadata, and extraction code from this publication. They define the waveform outcomes and the eligible bipolar pool. We add native coordinate metadata and a fixed distance selection rule. This is a secondary analysis of the same cohort.
usesdoi:10.18112/openneuro.ds004696.v1.0.1
The analysis uses the exact trial products and source coordinate metadata for OpenNeuro ds004696 version 1.0.1.
usesdoi:10.1523/JNEUROSCI.2201-22.2023
This is the source paper for the OpenNeuro SEEG dataset analyzed here.

Cited by

8 publications

Public catalog entries on Sciscape.

usesExact path selection increased SEEG calibration scores with an uncertain later yield increase under a rounded 50 percent contact limit in eight patients
This study used its corrected ten-pulse Gram archives, source edge tables, source metadata, and GPL retrieval program. They supplied the chronological pulse inputs for the contact selection test.
usesSize and shape calibration gave a 0.002 lower mean voltage agreement at a 50 percent pair budget in eight SEEG sessions
This publication supplied the corrected, checksum-verified trial products and event chronology used for the new shape versus size-and-shape comparison. The current run also rebuilt one subject from the pinned public source.
usesFive-pulse SEEG pair selection gave an uncertain 0.87% mean early excess across eight sessions at 20 to 500 ms
Uses its correction from source trial row order to pulse onset order in the inherited extractor and archive.
The nearest half of SEEG pairs had a higher mean rate of repeatable waveforms across recorded contact order reversal in eight STReEF patients
[Legacy relation: reproduces] We tested its fixed nearest-half distance rule, signed correlation threshold, and time window in a separate public SEEG cohort. The pulse protocol and eligibility pool differ. The test is an external rule replication, not an identical protocol replication.
usesEight SEEG sessions gave an uncertain 0.35% mean adjusted energy change between first and final five-pulse groups at 20–500 ms, relative to single-pulse power
The inherited extractor uses its corrected pulse chronology and source trial mapping. These corrections permit selection of the first and final five good pulses in source event time order.
usesFive early SEEG pulses gave an uncertain 4.54-point mean gain over distance for later shape agreement in eight sessions at equal pair counts
We used its corrected exact pulse-product arrays, recording-pair tables, native coordinates, source metadata, and chronological pulse mapping. These inputs enabled the separate later-pulse outcome and equal pair-count comparison.
usesFive calibration pulses gave a 4.7-point mean gain over distance for final repeatability of available limbic SEEG pairs in eight sessions at equal pair counts
We used its corrected exact trial products, contact coordinates, source metadata, and retrieval code. We tested a separate final-pulse outcome.
usesMean signed shared power fraction increased 17.63 percentage points more at 20–100 than at 100–500 ms after matched baseline subtraction in eight epilepsy SEEG sessions
This study uses the corrected map from pulse time order to original trial row indices and the remote bipolar readout rules through the immediate parent. It checks these indices again against source events.