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A joint five-pulse test did not detect smaller adjacent SEEG waveform distances at 20 to 500 ms in eight patients

We tested pulse order in public OpenNeuro ds004696 version 1.0.1 data from eight epilepsy patients. The test used 886 bipolar readouts at 86 stimulation sites. It included 191 complete blocks of five source-good pulses. At 20 to 500 ms, the equal patient mean order score was 0.0032. The 95 percent patient bootstrap interval was -0.0178 to 0.0203. The upper-tail conditional order test gave p = 0.369987. The primary test did not detect smaller distances between adjacent pulses under the stated joint order assumption. The test assumes independent patients and joint invariance under one common slot permutation within each patient. The pre-pulse mean score was 0.0042. The package contains compact data, proof, source records, code, figures, and reproduction instructions. The score cannot identify a biological cause or an effective sample count. No brain-computer interface was tested.

stereoelectroencephalography · electrical stimulation · pulse order · waveform distance · permutation test · patient bootstrap · joint order invariance · OpenNeuro

Admitted 1 citing publication

References

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  1. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    We use the contact and site rules and the bipolar extraction method. We extend the extraction to all complete five-pulse blocks.

  2. usesLater pulse variation accounted for 72.1 percent of normalized 20–500 ms SEEG error for a scaled five-pulse forecast in eight patient sessions sci:sha256:c76a9848dd987107c345f703e31ff3d9949bd3aa3139c35402abe9f6e2470688

    We use the source file hashes, source metadata, and processing code. We check our first and final block matrices against the archived matrices.

  3. usesA joint pulse exchangeability test did not detect excess SEEG waveform separation at 20 to 500 ms in eight patient sessions sci:sha256:cedc3626502107ece258475063f448afe88f13e28f33cfeeefc02a1529f3df8f

    The joint patient permutation method informed this test. Our test compares adjacent distances within every complete five-pulse block.

  4. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis uses processed trial waveforms from OpenNeuro ds004696 version 1.0.1.

  5. doi:10.1523/JNEUROSCI.2201-22.2023

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