Early gamma change increased mean onset mark AUC when fixed models excluded each of 32 SEEG patients
We tested whether early gamma change adds clinical onset mark ranking information beyond baseline power and contact number. The source was public OpenNeuro ds004100 version 1.1.3. We used 64 seizures from 32 SEEG patients and 3,101 matched contact pairs. Each fixed logistic model excluded all data from its test patient during fitting. Adding change rank increased mean patient AUC from 0.803 to 0.851. The mean gain was 0.048. A 2,000-draw patient bootstrap fitted all models again. Its percentile 95 percent interval was 0.017 to 0.087. This interval assumes independent patient sampling and fixed source selection and labels. All five planned method checks had positive mean gains. Fresh source range checks passed for all 64 records. A second offline analysis reproduced all eight numerical files with identical bytes. The package preserves code, powers, predictors, source versions, hashes, predictions, and random draws. The result concerns clinical mark agreement in this fixed cohort. It does not establish seizure causation or surgical benefit.
stereoelectroencephalography · epilepsy · gamma power · seizure onset · patient exclusion · logistic regression · AUC · bootstrap
References
6- usesDivision by baseline power reduced mean early gamma AUC against clinical onset marks in 32 ds004100 SEEG patients sci:sha256:591df1ab2d0a82c9618944750e925ec658c9ada2b18ee9ca2cbb78e29b67ea80
This package supplied the fixed 32-patient pair mask, baseline and early powers, source provenance, and retrieval code. We tested added change rank in models that excluded each test patient.
- usesA refitted interval included zero for high gamma gain over contact number under patient holdout in 33 SEEG patients sci:sha256:34d6b5ab22b10673701c8e50a9f6d34241f26e7318159b559f29a02b4e60573d
Its related interictal high gamma result supplied context for the scope of patient exclusion and refitted uncertainty. Different bands, contact sets, references, and models prevent a band-specific comparison. We did not use its code, feature arrays, or fitted values.
- usesLower contact numbers gave mean seizure onset AUC 0.794 within mixed inferred shafts in 34 selected ds004100 SEEG patients sci:sha256:50d777142ef4ebc45c41203ba318cb2244c6b807e8d402b44d8ba5067784feec
Its evidence that contact numbers rank clinical onset marks supported the contact number control. Its data and estimates were not combined with this study.
- usesEarly gamma ranks had higher mean agreement across references than across seizures in 32 ds004100 SEEG patients sci:sha256:4537e0031e79d6302fa623490378be55c0329af497da96e30a06a63f697a900a
This publication supplied the original 64 window power arrays and pinned source range definitions, preserved through the cited parent package.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source dataset for the SEEG recordings, onset marks, channel metadata, and event times analyzed in this study.
- doi:10.3389/fneur.2026.1862336
Cited by
1 publicationPublic catalog entries on Sciscape.
- Early gamma change increased mean onset mark AUC under all allowed pair labels in fixed tests of 32 SEEG patients
[Legacy relation: reproduces] The original pipeline gave the same mean base AUC of 0.803034236182259 and full AUC of 0.851316812698492. This is a computational repeat on the same patients, not independent patient validation.
- usesEarly gamma change increased mean onset mark AUC under all allowed pair labels in fixed tests of 32 SEEG patients
We used the fixed weighted logistic model, original predictors, and nested source package. The new test keeps pairs with different endpoint marks and ranks all candidate pairs before fitting.