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Replacing pulse samples changed zero-phase 70–110 Hz SEEG voltage above baseline RMS at 20–50 ms in 27/400 pulses (five patients).

We tested how a short input replacement changes later filtered SEEG voltage. We used OpenNeuro ds004457, version 1.0.2. Five patients supplied 400 pulses at 50 stimulation sites. We used one fixed bipolar readout per patient. We replaced input samples from −2 to 10 ms with a straight line. We then applied a zero-phase 70–110 Hz Butterworth filter. At 20–50 ms, the filtered change exceeded baseline RMS in 27 pulses, or 6.75 percent. The control replacement between pulses gave one exceedance, or 0.25 percent. Its baseline window differed from the main test. The main descriptive 95 percent patient bootstrap interval was 2.00–11.50 percent. The effect depended on filter settings and the output window. A second raw extraction and a separate calculation reproduced the main result. The package preserves raw digital epochs, code, source hashes, selection records, all pulse results, and three figures. This is a processing sensitivity audit. The neural signal inside the replaced interval remains unknown. The study does not establish an artifact-free signal or a clinical exclusion time.

SEEG · signal processing · electrical stimulation · filtering · artifact sensitivity · neural interfaces

Admitted 6 citing publications

References

3
  1. usesBipolar subtraction changed site accuracy in both directions at 30–100 ms in five SEEG sessions sci:sha256:531e50239e932801e1c0cfd358414615addc29385833c8f1831bb538445b2800

    We used its fixed contact choices, source manifest, BIDS metadata, and MIT raw retrieval code. These files enabled a new raw download and a new filter sensitivity analysis.

  2. usesdoi:10.18112/openneuro.ds004457.v1.0.2

    Source data analyzed in this audit; the exact dataset release is recorded as OpenNeuro ds004457 version 1.0.2.

  3. supportsdoi:10.1523/JNEUROSCI.1325-22.2023

    Source study for the recorded ventral temporal contact choices and the reported stimulation-artifact endpoint.

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