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Mean high gamma AUC within inferred shafts exceeds a label control in one-minute SEEG samples with an average reference from 33 HUP patients

We tested whether high gamma power agrees with clinical seizure onset labels within inferred SEEG electrode shafts. We used two one-minute records from each of 33 eligible HUP patients in OpenNeuro ds004100 version 1.1.3. The score used an average reference without onset labels. Mean within-shaft AUC was 0.7037, with a 95 percent patient bootstrap interval of 0.6329 to 0.7701. A control kept each shaft label count fixed. Its mean AUC was 0.4999. The one-sided test gave Holm-adjusted p = 0.0002 under within-shaft label exchangeability. Mean all-contact AUC was 0.6286. Restriction to mixed-label shafts explained most of the apparent AUC increase. The comparison change on the same contact set was 0.0106, with an interval that included zero. The package preserves code, covariance inputs, source versions, hashes, all patient results, and raw retrieval instructions. These short samples test source label agreement. They do not establish clinical value.

stereoelectroencephalography · intracranial EEG · high gamma power · seizure onset labels · area under the curve · electrode shafts · conditional permutation test

Admitted 1 citing publication

References

3
  1. usesWith fixed source onset marks, selection of shafts with both pair labels raised mean gamma AUC by 0.174 in 31 HUP SEEG patients sci:sha256:b63b81fb8210fdf5f6fd9cac5301edde878a500ca236c2722ede2a1650347d18

    After our main results, we read its contact selection audit for bipolar pair scores. It informed the report of two explicit parts of our planned mixed-contact control. We added descriptive differences and intervals. We used no numerical inputs from this publication. Both studies use the same source cohort.

  2. usessci:sha256:ad80bc2bd0737883d3eb45a01e266fee6a996e9e1e541f80de6ada0bdd0447e5 not known to Sciscape

    We use 70 verified one-minute band covariance inputs from 35 HUP patients, with the source metadata, channel checks, fixed selections, and pinned raw retrieval code. These inputs allow fixed-score tests within inferred electrode shafts. We use an average reference that does not use onset labels.

  3. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analyzed SEEG records and source labels come from HUP iEEG Epilepsy Dataset, ds004100 version 1.1.3.

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