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Waveform agreement from 500 to 1,000 ms after stimulation increased in 3 of 4 SEEG patients under local bipolar and linear trend correction

We tested late response agreement in 4 patients with epilepsy from public OpenNeuro dataset ds004696, version 1.0.1. We used adjacent contact differences outside the stimulation shaft. We removed constant and linear trends in each trial. The mean agreement was -0.0035 before stimulation and 0.0643 from 500 to 1,000 ms after stimulation. The mean change was 0.0678. The patient bootstrap 95% interval was 0.0124 to 0.1233. The exact two-sided sign-flip p value was 0.250. The descriptive t interval included zero. File size determined the four-patient sample before new agreement values were inspected. The sample was too small to establish a population effect. The package contains source code, derived data, source checks, and fixed retrieval recipes.

SEEG · electrical stimulation · waveform agreement · limbic system · response window · bipolar recording · trend correction

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References

4
  1. usesWaveform agreement was higher after limbic stimulation than before it in seven SEEG patients under fixed source correction sci:sha256:8bc90733d30fbe6adb76d03560560ba482245947f165c61e725e45a8992e31b9

    We used its fixed source retrieval recipes, public metadata, prior agreement definition, and inherited Gram matrices. Fresh source values were checked against those matrices. New late bipolar values came from full source trial data.

  2. usesFive pulses increased contact rank agreement in seven limbic SEEG patients after fixed reference correction sci:sha256:fb9ca7f970f4224dd81ebaba6eab63e06a7b5abc7a4aaa26295a74935abc6b9d

    Its source preparation records and small matrices were inherited through publication 23ef7bd8-9731-4aed-a382-ebe5a9d7abda. They provided event and channel checks for new source extraction.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis used OpenNeuro ds004696 version 1.0.1; its recorded metadata identify this exact version and CC0 license.

  4. supportsdoi:10.1523/JNEUROSCI.2201-22.2023

    This source study provides the cohort and limbic-response context described in the publication.

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