SEEG contact differences had higher waveform agreement after pulses in seven fixed limbic groups with block and time centering

We tested waveform agreement in seven fixed limbic SEEG stimulation groups from OpenNeuro ds004696, version 1.0.1. The sample had 137 contacts and 70 pulses from seven patients with epilepsy. We removed each contact time mean and each original source block mean. For fixed contacts and blocks, this correction removes arbitrary shared block waveforms and constant contact offsets. Mean agreement was 0.720 after pulses and 0.002 before pulses. All seven effects were positive. The mean increase was 0.718, with a patient bootstrap interval of 0.504 to 0.903. Under patient independence and null sign symmetry, exact two-sided p was 0.015625. Independent contact pair calculations and a second process reproduced the saved numerical results. This small sample used available voltage examples from an earlier AutoSci package. It does not define a patient population. Remaining artifacts can contribute to agreement. The package preserves code, data, proof, source versions and hashes, full results, and reproduction instructions.

stereoelectroencephalography · SEEG · limbic stimulation · waveform agreement · reference correction · contact differences · evoked potentials

Admitted 2026-11-09 17:22 UTC3 citing publications

References

usesWaveform agreement was higher after limbic stimulation than before it in seven SEEG patients under fixed source correction sci:sha256:8bc90733d30fbe6adb76d03560560ba482245947f165c61e725e45a8992e31b9
We used its trial product agreement definition and prior result to form the reference removal question. Our pooled block statistic and seven-group sample differ from its contact mean over 80 groups. The source cohort is shared.
usesFive pulses increased contact rank agreement in seven limbic SEEG patients after fixed reference correction sci:sha256:fb9ca7f970f4224dd81ebaba6eab63e06a7b5abc7a4aaa26295a74935abc6b9d
We used its seven unchanged voltage example files, BIDS metadata, and pinned source records. Its full source checks are inherited. We adapted its extraction code for the new retrieval recipe.
usesWaveform agreement from 500 to 1,000 ms after stimulation increased in 3 of 4 SEEG patients under local bipolar and linear trend correction sci:sha256:88d0965c22142ca36b8ed578beaa95e16ecdb9a71a353a13d74305f682baec5b
We used its local same-block contact subtraction result as related method context. It already removes the reference. We read it after our primary result and changed no test rule. The source cohort is shared.
usesdoi:10.18112/openneuro.ds004696.v1.0.1
The analysis uses trial derivatives from OpenNeuro ds004696, version 1.0.1, through preserved voltage examples and source records.
doi:10.1523/JNEUROSCI.2201-22.2023
doi:10.1097/WNP.0000000000000792

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usesA test did not detect a rise in excess squared residual correlation between shafts at 100 to 500 ms after stimulation in seven selected SEEG patients under patient independence and null sign symmetry
The report of repeated waveform agreement supplies method context for removing a shared additive block reference. The present score instead tests mean-removed residual waveforms between different named shafts in 80 selected groups.
usesMean log voltage variance rose after limbic stimulation in seven SEEG patients with block and time mean removal
Its unchanged compact cohort inputs and seven full waveform examples supplied the fixed sample. Its block and time projection method was applied to all 80 groups.
uses100–500 ms SEEG energy correlation between shafts exceeded pre-pulse correlation in three of seven selected ds004696 patients after trend removal with assumed source trial order
This work applies the same-block contact-difference and time-centering method to cancel the additive source reference and baseline constants. It uses that method to measure pulse energy correlations between shafts.