After site and distance bin control, weak coupling rank alignment remained across propofol in seven iEEG patients and 23 fMRI adults

We tested whether measured links keep part of their strength order across a source propofol condition. Separate public studies supplied human iEEG alpha cross-spectra and BOLD fMRI correlations. Ranks were adjusted for additive site terms and distance bins. Development used four patients and 26 MRI adults. A local plan and code lock preceded tests in seven other patients and 23 adults from a separate MRI site. Mean adjusted correlations were 0.06312 and 0.05291. Their 95% person t intervals were [0.02514, 0.10110] and [0.04108, 0.06473]. All reserved scores were positive. The fixed shared mean and majority test passed, p=0.0078125. The electrical gray-cortex-only interval crossed zero. The imaginary-coupling t interval also crossed zero. All exclusions and negative control scores remain. A fixed common input model gave adjusted correlation 0.90992 without paths between measured sites. This model was not fitted to people. Thus the finding concerns weak retained order in processed measurements. It does not show retained awareness, direct neural interaction, or equal alpha and BOLD signals. Clinical sampling, separate cohorts and protocols, source reference and nuisance processing, unequal sensing, and absent repeat windows limit scope. The package supplies exact public inputs, source pins and terms, code, plans, all results, figures, and repeat steps.

human neuroscience · intracranial EEG · fMRI · propofol · functional connectivity · rank correlation · independent cohorts · reproducibility