A SEEG distance and time test did not detect a local high gamma excess after negative motor stimulation in 15 patients

We tested local high gamma power changes in public SEEG data from OpenNeuro ds006519, version 1.0.0. The test used 22 records from 15 patients with negative motor responses. Near channels were within 20 mm of the stimulated pair. Distant channels were at least 40 mm away. We compared absolute power changes across selected before and after intervals with changes within each interval. The planned patient mean was -0.10 dB. Its 95 percent bootstrap interval was -0.62 to +0.34 dB. All eight fixed sensitivity intervals included zero. An exact calculation showed that channel medians can bias this temporal score under exchangeable time labels. We preserved the planned result and added arithmetic means. The added estimate was -0.18 dB, with an interval of -0.66 to +0.24 dB. Independent checks verified all 355 source files and rebuilt all 65 stored epoch pairs. The package contains signals, source hashes, code, result tables, figures, and reproduction instructions. Missing site coordinates excluded 13 records. No sham or movement timing was available. The result does not exclude a rapid stimulation response or establish a cause.

stereoelectroencephalography · high gamma · negative motor response · intracranial EEG · distance analysis · temporal control · bootstrap · estimator bias