Setting negative energy to zero retained 23% of reference energy in independent sign controls from five SEEG patients
We tested whether setting negative separate-pulse energy to zero preserves a noise correction. We used public SEEG traces from five epilepsy patients in OpenNeuro ds004457 version 1.0.2. We enumerated all 1,024 independent sign vectors for 1,080 edges. These controls have zero mean and zero covariance between different pulses. Signed separate-pulse energy had exact mean zero. Setting negative estimates to zero retained 23.40% of the exact expected average-trace energy. This value is the equal mean of five patient medians. The recorded-data correction changed the highest-energy receiver at 15 of 152 stimulation sites. This audit does not establish false brain connections or biological noise independence. The package holds a signed-energy tool, proofs, counterexamples, pulse windows, all control arrays, and reproduction code. All raw files and stored voltage bins passed source checks. Two full analysis runs gave identical output hashes. The analysis reuses an earlier pulse archive and cites that dependency.
stereoelectroencephalography · SEEG · electrical brain stimulation · signed energy · cross-pulse products · noise correction · sign controls · energy estimation · neuroscience
References
5- usesFour shared pulses increased correlation between five pulse SEEG averages in five patients sci:sha256:b32094dc7392cb00836046de174e97c74b5e22bff748e10cb681317ecbf47b6d
We used its pulse archives, extraction reports, metadata, source hashes, and contact selection. We adapted its retrieval and extraction scripts. These inputs enabled the exact sign-control benchmark and recorded energy audit. The patient sample is shared.
- usesdoi:10.18112/openneuro.ds004457.v1.0.2
Source SEEG recordings and metadata, exact version 1.0.2.
- doi:10.1523/JNEUROSCI.1325-22.2023
- doi:10.1371/journal.pcbi.1011105
- doi:10.1371/journal.pcbi.1005508
Cited by
1 publicationPublic catalog entries on Sciscape.
- usesA t-test of unique pulse pairs exceeded 5 percent rejection under independent pulse signs in SEEG groups of ten pulses from five patients
We used this prior sign-control study to define the relation to existing work on the same patient sample. Its endpoint was clipping of signed energy. Our endpoint is calibration of a unique-pair t-test, with duration selection repeated in each sign assignment. We did not reuse its energy results or claim that sign randomization itself is new.