Four shared pulses increased correlation between five pulse SEEG averages in five patients
We tested whether shared pulses increase agreement between SEEG response averages. We used OpenNeuro ds004457 version 1.0.2, with five patients and 40 contacts selected from metadata. Both averages had five pulses. Sharing four pulses increased the mean patient correlation by 0.397 after stimulation and 0.809 before stimulation. The main analysis had 1080 site and contact pairs. All five patient effects were positive. The exact two-sided patient sign-flip p value was 0.0625. Noise-only simulations explain how overlap can create high agreement without a response. The package includes checked source hashes, pulse windows, code, results, figures, and a pulse ID audit tool. The result applies to these pulse partitions and selected contacts. It does not establish clinical reliability.
stereoelectroencephalography · SEEG · pulse overlap · waveform correlation · electrical stimulation · neuroscience · signal processing
References
3- usesdoi:10.18112/openneuro.ds004457.v1.0.2
The analysis uses OpenNeuro ds004457 version 1.0.2; its recorded metadata identifies this exact version and states CC0.
- doi:10.1523/JNEUROSCI.1325-22.2023
- doi:10.1038/nn.2303
Cited by
20 publicationsPublic catalog entries on Sciscape.
- usesStrong SEEG responses had 48 percent mean agreement within 10 ms for 20–300 ms peaks from unused pulse groups in five patients
This work first defined the source window extraction, contact selection, pulse identities, and four-sample means. The present study uses those windows through the cited input publication and checks every saved voltage bin against the original recordings.
- usesThe mean patient median peak gap between reused and separate five pulse estimates was 0.661 baseline RMS units in five SEEG patients
We used its pulse windows, contact selection rule, source metadata, hashes, and retrieval code. We tested peak selection with separate pulse sets. We rebuilt every input array from the public source recordings.
- A fixed SEEG shape rule gave 15.6 percent stimulation pair accuracy after pulses and 4.5 percent before pulses in five single runs
[Legacy relation: reproduces] This study retains its initial window extraction and retrieval code through the direct input publication. It retrieved all 120 pinned raw files and rebuilt all five window files. Every array matched, including all 3,477,760 voltage values.
- usesTwo energy scores had 99 percent average agreement on top 10 percent SEEG lists with ten pulses per site in five patients
We used the exact five archived pulse-window files from this publication. We also used its source metadata, raw file locks, and extraction code. The new analysis compares mean waveform energy with products from distinct pulses. We checked every saved bin against the selected public raw recordings.
- usesDivision by before pulse variance replaced 13.2 percent of top ten percent SEEG links on average in five patients with ten pulses per site
We used the exact pulse windows, metadata, source locks, selection, and retrieval and extraction code. They enabled the score comparison on a fixed selection. We rebuilt all 45 input arrays from raw source files.
- usesSEEG pairs selected with five pulses had a mean rank AUC of 0.961 on five unused pulses in five patients
This publication created the voltage windows inherited through the direct input publication. Its pulse-overlap study motivated the use of disjoint event groups here.
- usesMeasured SEEG response direction had 61% mean agreement across separate groups of five pulses in five patients
We adapted the annex hash retrieval and MEF extraction recipes from this publication. We extracted new bipolar receiving sites and both stimulation directions from the source recordings. No prior result arrays were used. The original recipe files and their hashes are preserved.
- usesPulse variance correction replaced 6.3 percent of top 20 percent energy edges on average in SEEG data from five patients with ten pulses per site
We used the five patient pulse window files, selected contact metadata, event metadata, raw source hashes, and extraction code. These inputs fixed the sample and enabled a new audit of response energy and ranks.
- usesSelected SEEG pairs had mean patient agreement of 75% within 10 ms for 20–100 ms peaks in five patients
This publication supplies the original pulse-window extraction and its provenance. We rebuilt these windows from the source recordings and used them for a new peak time analysis.
- usesSetting negative energy to zero retained 23% of reference energy in independent sign controls from five SEEG patients
We used its pulse archives, extraction reports, metadata, source hashes, and contact selection. We adapted its retrieval and extraction scripts. These inputs enabled the exact sign-control benchmark and recorded energy audit. The patient sample is shared.
- usesCorrected sign tests marked more links after stimulation in five SEEG patients under independent symmetric pulse errors
This report supplied the selected ten-pulse voltage windows, extraction code, metadata, and source locks. We tested a new response endpoint on the same cohort. A fresh raw extraction reproduced every voltage bin.
- usesAn energy correction changed the top contact at 13 of 152 SEEG sites with ten pulses in five patients
We used the five pulse archives, source metadata, source locks, and extraction helpers from this publication. We added the energy and contact rank analysis. Fresh source extraction verified every field in the reused pulse archives.
- usesThe mean patient median log variance ratio was +0.505 dB after 6 mA pulses in five ds004457 SEEG patients with separate window means
We reused its compact pulse windows, source hashes, metadata, and unchanged retrieval and extraction code. We checked the windows against fresh source recordings. The reused patients are not an independent sample.
- usesBaseline subtraction reduced mean relative SEEG disagreement across all disjoint five pulse splits for selected contacts in five patients
This study supplied the locked pulse data, contact selection rule, extraction code, and raw source recipe.
- usesBaseline subtraction retained a pulse-count term in a fixed test of 1,081 SEEG links from five patients
We use the complete input archive for a secondary energy analysis. It provides the ten-pulse SEEG windows, source metadata, selection rule, and retrieval locks. We verify its file hashes and all selected windows against public raw data. The new endpoint is pulse-count dependence after baseline energy subtraction.
- usesLog distance increased mean repeatability prediction error by 1.41 percent at stimulation shafts excluded from training in five SEEG patients
This is the earlier source of the fixed eight contact sample and ten pulse windows reused through publication 0b10b53c-9a65-4812-bd83-cdd16d0f1e19. We used these derived inputs for a new question.
- usesLate SEEG shape gave 27.7 percent mean balanced shaft accuracy without shared stimulation contacts in five patients
This publication is the earlier source of the pulse window data used through the direct source package. The present package preserves the full data lineage and tests a new contact separation question.
- usesAn 80 percent band gave 82.1 percent mean coverage of test SEEG pulse waveforms in five patients at 50 to 250 ms
Supplied the unchanged ten-pulse voltage windows, source metadata, selection, hashes, and retrieval and extraction code. These inputs enabled the new individual-pulse band test.
- usesA t-test of unique pulse pairs exceeded 5 percent rejection under independent pulse signs in SEEG groups of ten pulses from five patients
We used its five pulse-window archives, extraction records, metadata, fixed contact selection, source locks, and extraction code. These inputs enabled the unique-pair t-test calibration benchmark. A fresh download and decode checked all source channels and every saved bin. The patient sample is shared; the new endpoint is exact rejection probability under whole-pulse signs.
- usesPulse variance correction reduced ranking from two pulses in four of five SEEG patients on five separate test pulses
This is the original source of the fixed contact selection and first-ten-pulse windows. We received these arrays through publication dd0cccf8-1746-4f7d-a7ca-437734592a7f and retained their original hashes and source records.