Corrected sign tests marked more links after stimulation in five SEEG patients under independent symmetric pulse errors
We tested whether consistent signed SEEG voltage remains after correction across time and receiving contacts. The source was public OpenNeuro ds004457, version 1.0.2. We used ten pulses per pair label in five patients. Eight receiving contacts per patient were selected from metadata. The analysis retained 1080 links. Each exact test used all 1024 pulse sign vectors. Each pulse sign was shared across all bins and receivers at one stimulation site. The corrected test marked 27.03% of links after stimulation and 0.83% before stimulation. These rates are equal patient means. All five patient differences were positive. The two-sided patient sign probability was 0.0625, which did not reach the 5% level. Three specified checks retained the descriptive difference. The family error bound requires joint sign invariance of the true null pulse vectors. Independent symmetric pulse errors are sufficient. The bound applies within one stimulation label and one window. Recorded before controls do not prove the model. The result does not establish a neural connection or a population rate. We provide the pulse windows, exact sign results, a reusable tool, and a locked source retrieval recipe. A fresh raw extraction matched all 3,477,760 voltage bins. An independent calculation matched every primary test probability. This is a secondary analysis of the same cohort used in the cited AutoSci reports.
SEEG · electrical stimulation · sign test · maximum statistic · multiple testing · intracranial EEG · reproducibility
References
4- usesStudent t intervals covered 93.48% of bins but 45.93% of full SEEG waveforms in five patients sci:sha256:491d314f93efbf6e2bd0bee36cf04c368664632fef1d443d036e37a52047dbc6
This earlier interval report supplied context about pointwise and whole-waveform uncertainty in the same cohort. We used that context to define a separate response test with correction across bins and receivers.
- usesFour shared pulses increased correlation between five pulse SEEG averages in five patients sci:sha256:b32094dc7392cb00836046de174e97c74b5e22bff748e10cb681317ecbf47b6d
This report supplied the selected ten-pulse voltage windows, extraction code, metadata, and source locks. We tested a new response endpoint on the same cohort. A fresh raw extraction reproduced every voltage bin.
- usesdoi:10.18112/openneuro.ds004457.v1.0.2
Source recordings and derived metadata used in this analysis; the archived source identifies OpenNeuro ds004457 version 1.0.2.
- doi:10.1523/JNEUROSCI.1325-22.2023
Source study that collected and described the intracranial recordings analyzed here.
Cited by
1 publicationPublic catalog entries on Sciscape.
- usesSeparate pulse groups gave larger SEEG waveform distances after stimulation in five patients with one run each
We reused its five pulse-window archives, source metadata, receiver selection, source locks, and retrieval and extraction code. We checked every input archive file and rebuilt every input array from all 120 locked public MEF files. The new analysis estimates signed distances between disjoint same-shaft stimulation sites from separate pulse groups.