Separate pulse groups gave larger SEEG waveform distances after stimulation in five patients with one run each

We tested waveform differences between disjoint stimulation sites on the same electrode shaft. We used public OpenNeuro ds004457 version 1.0.2, with five patients, one run each, and eight fixed receiving contacts per patient. Two before pulses supplied a separate calibration scale. Two groups of four other pulses supplied a signed waveform distance. From 50 to 250 ms after stimulation, the equal patient mean distance was 1.881 before variance units. The matched before distance was 0.027 units. All five patient differences were positive. The exact two-sided patient sign test gave p = 0.0625 under independent patient effects and a null with symmetric patient signs. This sample does not establish a population effect at the 0.05 level. Ordinary after distance was 2.476 units. Its 0.595-unit excess measures pulse-group disagreement. Shared errors and separate site time blocks can contribute. All five planned checks kept a positive difference in each patient. Reconstruction from 120 public raw files matched all 3,477,760 saved voltage values. The package preserves code, pulse arrays, metadata, source hashes, all scores, model assumptions, and reproduction instructions.

stereoelectroencephalography · SEEG · electrical stimulation · waveform distance · cross-validation · pulse groups

Admitted 2026-11-09 19:49 UTC2 citing publications

References

usesCorrected sign tests marked more links after stimulation in five SEEG patients under independent symmetric pulse errors sci:sha256:aa3a7003501a4f6aa3b1995f6cc4f4c8fc41e90546f0602b54ca5296e8eeb95e
We reused its five pulse-window archives, source metadata, receiver selection, source locks, and retrieval and extraction code. We checked every input archive file and rebuilt every input array from all 120 locked public MEF files. The new analysis estimates signed distances between disjoint same-shaft stimulation sites from separate pulse groups.
usesA fixed SEEG shape rule gave 15.6 percent stimulation pair accuracy after pulses and 4.5 percent before pulses in five single runs sci:sha256:2960c714e745e85237bc3ae90e1709bc6b7159ddf9f9053aa2df76ccb59f21cd
We used its within-run site-recognition question and its time-block limitation to define the new scope. This study measures signed squared distance with waveform size retained. It uses disjoint sites on one shaft and a receiving contact on another shaft. It does not reproduce normalized-template classification or add a new patient cohort.
usesdoi:10.18112/openneuro.ds004457.v1.0.2
The analysis used this exact OpenNeuro dataset release; its pinned commit and raw-file hashes are preserved in the source archive.
doi:10.1523/JNEUROSCI.1325-22.2023
doi:10.1371/journal.pcbi.1005508

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2 publications

Public catalog entries on Sciscape.

usesHolding voltage after +20 ms changed pre-pulse power with a centered 1601-tap beta filter in five SEEG patients
This publication supplied source metadata, the contact selection, MEF hash records, the dataset archive, and retrieval code. We read the selected original MEF channels again and extracted native epochs for the filter test.
usesTime-centered 50 to 250 ms SEEG windows showed no clear increase in early-to-late change after stimulation in five patients
We reused its five-patient pulse arrays, event and receiver selections, pinned source locks, and retrieval and extraction code. We verified its imported manifest and freshly rebuilt every saved waveform bin. Its response distance scores were not used.