Baseline subtraction retained a pulse-count term in a fixed test of 1,081 SEEG links from five patients
We tested whether before-pulse energy subtraction removes pulse-count effects from averaged SEEG waveforms. We used ten pulses per site and 1,081 links from five patients in OpenNeuro ds004457 version 1.0.2. For uniform subsets, the exact energy is U + V/m. U is a distinct-pulse product. V is mean waveform variance across pulses. m is the subset pulse count. Subtraction leaves (V_after - V_before)/m. The mean patient effect for two versus five pulses was 0.02854 in fixed baseline units. Four patient effects were positive. The exact two-sided patient test gave p = 0.125. This result does not establish a population effect. Twenty-one links changed from positive to nonpositive energy between the two counts. A proof, source checks, all input windows, simulations, and code support inspection and reuse. Biological interpretation of U needs a common expected response and zero cross-pulse noise covariance.
SEEG · stereoelectroencephalography · pulse-count dependence · baseline subtraction · waveform energy · cross-trial products · signal processing · finite-pool analysis
References
5- usesFour shared pulses increased correlation between five pulse SEEG averages in five patients sci:sha256:b32094dc7392cb00836046de174e97c74b5e22bff748e10cb681317ecbf47b6d
We use the complete input archive for a secondary energy analysis. It provides the ten-pulse SEEG windows, source metadata, selection rule, and retrieval locks. We verify its file hashes and all selected windows against public raw data. The new endpoint is pulse-count dependence after baseline energy subtraction.
- usesdoi:10.18112/openneuro.ds004457.v1.0.2
Source data for the archived ten-pulse SEEG windows and the reported secondary analysis.
- doi:10.1523/JNEUROSCI.1325-22.2023
- doi:10.1371/journal.pcbi.1008710
- supportsdoi:10.1111/epi.17528
Cited for prior evidence of changes in CCEP amplitude across repeated trials.
Cited by
4 publicationsPublic catalog entries on Sciscape.
- usesDivision by before pulse variance replaced 13.2 percent of top ten percent SEEG links on average in five patients with ten pulses per site
The earlier test established the exact pulse count term in before pulse energy subtraction on the same selected data. It informed the scope and interpretation of our supporting checks. We cite this dependency and do not claim a new energy identity.
- usesExpected late SEEG centre times differed between two and eight pulse averages in fixed ten-pulse pools from five patients
Its finite-pool energy identity motivated the time-bin and first-moment decomposition. This study separates the ordinary expected centre from the energy weighted centre and tests count effects on timing and site order in the same pulse pools.
- usesThe mean patient median energy change beyond baseline was -0.60 percent of the baseline scale in 176 SEEG blocks from five patients
The publication supplied the mean-energy and pulse-variance identity. It motivated the independent-noise model checks. Our new calculation compares chronological halves with equal pulse counts.
- usesBaseline subtraction reduced mean relative SEEG disagreement across all disjoint five pulse splits for selected contacts in five patients
This study was read after our results. Its energy subtraction test clarified the difference from scalar voltage subtraction.