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A four-site diversity rule did not pass a shared gain test for sound matching in six SEEG patients and 16 fMRI adults

We tested whether response diversity improves the choice of four auditory sites beyond repeatability alone. Separate public studies supplied SEEG high-gamma amplitude and BOLD fMRI. Two patients and four MRI adults supplied development. A local plan and code lock preceded new endpoint tests in six other patients and 16 other MRI adults. An added MRI study supplied eight other adults. Each split used 32 calibration sounds, 16 candidate sites and 96 test sounds from a source nonvoice group. A fixed greedy determinant rule balanced quality and diversity. Mean gains were 0.546, 3.496 and 2.656 percentage points. The SEEG 95% person Student limits were [-0.009, 1.102]. The required interval gate failed. The electrical exact sign-flip p was 0.0625. All 24 target MRI gains were positive. The full shared superiority rule failed. Eight-site selection and added baseline subtraction reversed the electrical gain. All negative people and controls remain. An exact limit makes the selectors equal for parallel estimated tuning profiles. A noisy one-direction model lost accuracy; stable measurement terms could also produce a benefit. This is a retrospective tool benchmark in source-screened sites. It does not establish a common neural cause, equal signal content or an implant benefit. Cohorts, libraries, source selection, initial pool size and measurement filters limit transfer. Code, provenance, performance data, figures and repeat steps are supplied. Neural arrays stay external.

auditory cortex · SEEG · fMRI · site selection · response diversity · repeatability · natural sounds · negative result

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References

13
  1. usesRemoving the half of selected sites with the highest fitting reliability decreased sound assignment accuracy more than random removal in six SEEG patients and two fMRI panels sci:sha256:a37bce91226396be1e52f1daa4589f39b2fcd31484268e8bace176f0e590143c

    Its reliability-based removal benchmark motivated the stronger matched-count comparison.

  2. usesFor 128 nonvoice sounds per study and fixed references, mean repeat area scores were positive in six SEEG patients and 24 fMRI adults sci:sha256:200641dbb520b35d79aa7a618d469b63a67f22fb52ce49c4f7c09bd72b569da4

    We reuse its source readers, exact source pins and grouping rules.

  3. usesFixed maps of 128 sounds gave positive mean agreement in six SEEG patients and two fMRI groups sci:sha256:5690b51341d3a75d7b200065730029a58f37ac0bcf2cb4ee186b43043aab88fb

    The reused reader retains this source-code attribution chain.

  4. usesA fixed rank test did not confirm shared sound map identity matching across different sites in eight SEEG patients and 28 fMRI adults sci:sha256:14ea20e6b74eeb1fa3709a8dd4dd439db380cd96a3c2db684eb25c522c7f8352

    The reused reader retains this source-code attribution chain.

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