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A single-cell loss could halve model conductance in 31 to 36 percent of path-preserving pairs in two partial worm maps

We tested a passive electrical model in two partial adult C. elegans brain maps. For each endpoint pair, we deleted each other cell in turn. Among pairs that kept a path after every such deletion, 2159 of 5946 in adult 7 (36.31 percent) and 2198 of 7170 in adult 8 (30.66 percent) lost more than half their effective conductance after at least one deletion. With unit conductance per link, the shares were 26.03 and 23.46 percent. Common-node graphs gave 33.30 and 24.35 percent. Bilateral partners had lower descriptive shares, without degree or spatial controls. Their worst-retention ranks had correlation 0.506 across 42 shared qualifying pairs. Independent traversal and grounded equations checked the results. Incomplete electrical annotation, two partial maps, and passive model assumptions prevent claims about live-animal lesions or reliable representations. Code, pair tables, lesion tables, source hashes, and retrieval steps support reproduction.

C. elegans · gap junction · effective conductance · cell loss · circuit robustness · passive model

Admitted 5 citing publications

References

7
  1. usesdoi:10.1038/s41586-021-03778-8
  2. usesdoi:10.1371/journal.pcbi.1001066
  3. reviewshttps://www.nas.ewi.tudelft.nl/people/Piet/papers/LAA_2011_EffectiveResistance.pdf
  4. usesLocal eigenmode scores missed high-impact link removals in passive models of two partial adult worm electrical maps sci:sha256:8f4b7d181847ef8f3041d8da43d958d686f76b5b6744ad472e2152ec8232d5fb

    Uses its common-neuron selection as context; replaces link-loss spectral tests with cell-loss pair conductance tests. No code or result tables were reused.

  5. reviewsMean short-route backup of bilateral neuron pairs remained after weak-edge removal in two adult worm connectomes sci:sha256:668597ed9fe04c679f2d61e27aa253a776b0a47f0b1af77171c5ab4efb56fd33

    Related bilateral chemical-route backup test. The present study measures electrical conductance after single internal cell loss.

  6. useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_7.csv
  7. useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_8.csv

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