Later 20 to 100 ms SEEG variance outside a shape fitted from four pulses was 1.20 times the variance before pulses at 138 sites in five patients
We tested voltage variation after 6 mA stimulation at 138 sites in five patients with epilepsy. We used OpenNeuro ds004457 version 1.0.2. Four early pulses fitted one response shape for each recording pair. Four distinct later pulses measured variance. In the 20 to 100 ms window, variance outside that shape was 1.201 times the variance in a matched window before pulses. Each patient had the same weight. The descriptive patient bootstrap interval was 1.112 to 1.300. All five patient ratios exceeded one. The exact two-sided sign-flip reference was 0.0625. A direction fitted before pulses gave little extra contrast. Error in the fitted shape can leave variation from a true response with one shape. The package contains voltage bins, source checks, code, three figures, and reproduction instructions. This test can support calibration research for brain interfaces. It does not establish a neural mechanism or a live interface benefit.
stereoelectroencephalography · electrical stimulation · trial variance · response shape · signal projection · brain-computer interfaces
References
6- Later 20–500 ms SEEG variance outside a shape from five pulses was 2.11 times the variance before pulses at 86 selected sites in eight people sci:sha256:d7334af97e9ceb52d52f038db543c405d40b5dc0dfc1e79213b2dbb0abf242bb
[Legacy relation: reproduces] We tested its fitted-direction residual variance principle in ds004457 with five patients, four fit pulses, four distinct later test pulses, and a 20 to 100 ms window. The primary residual ratio was 1.201. This is a conceptual replication with different recording targets and site rules. It is not an exact protocol replication or a controlled comparison of ratios.
- usesA contact mixture raised mean 20 to 100 ms site accuracy under hidden simulated contact errors at ten times the fitted voltage scale in five SEEG sessions sci:sha256:1fe087ca2edf92bb930844bed18a6b825f82b783043f5bfea4f0cbc51ef01231
We used its checked voltage bins, fixed recording target list, source metadata, and raw retrieval and extraction code. We rebuilt all five voltage archives from the pinned source objects. We kept the same patients and used a new site rule and variance outcome. This is not a new patient sample relative to that input publication.
- uses4–30 Hz SEEG variance remained greater after stimulation outside an early response plane in eight epilepsy patients sci:sha256:4e0a00e389aea5abca17ff3342ffafee0158c25370913bed80856b89e41ce7ae
We used its before-trained direction control principle. We applied one before-trained mean direction and one response-trained direction to the same later before and after voltage windows. The control/response residual ratio was 1.025, with no clear direction advantage. We did not implement its two-direction spectral estimator.
- usesdoi:10.18112/openneuro.ds004457.v1.0.2
Source recordings and voltage data analyzed in this study.
- usesdoi:10.1523/JNEUROSCI.1325-22.2023
Source study for the SEEG recordings.
- doi:10.1371/journal.pcbi.1011105
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