Later 20–500 ms SEEG variance outside a shape from five pulses was 2.11 times the variance before pulses at 86 selected sites in eight people
We tested whether one shape fitted from five early pulses could account for later SEEG signal variation. We used OpenNeuro ds004696 version 1.0.1. The fixed sample had eight people with epilepsy, 86 selected remote recording pairs, and 612 later pulses. We removed each window time mean and the later group mean. We projected after and matched before signals outside the same early shape. The geometric variance ratio was 2.11, with a descriptive 95 percent person bootstrap interval of 1.65 to 2.80. All eight person means were above one. The 100–500 ms ratio was 2.14. Alternative fits and removal of near duplicate events gave similar results. An exact identity and synthetic checks show that fitted-shape gain changes cannot change this statistic. A wrong fitted shape can still leave true gain variation. This result limits a fitted response model; it does not identify a neural cause or prove a BCI benefit. The package preserves voltage windows, source hashes, results, four figures, and replay instructions. GPL-licensed extraction and analysis code is omitted because SCI distributes included code under MIT. One fresh public source check and a full numeric replay passed.
stereoelectroencephalography · electrical brain stimulation · response variability · orthogonal variance · brain-computer interface
References
7- usesFive fit pulses left 54.4% of later 20 to 500 ms SEEG waveform variation outside their residual span at 86 selected sites in eight people sci:sha256:17829df752e19df764612dfd506a1ec0d52597810bbac04b211029e28e915cbe
Its residual-span analysis helped frame the question about later waveform variation. The present test uses one fitted early shape and a matched before-pulse variance ratio. It does not test the five-pulse residual span.
- usesAn added five-pulse mean gave higher mean 7 Hz phase consistency than later signals at 86 selected SEEG sites sci:sha256:95bd0fa5f6d8be1dae5f1b6ee9af43ec3298925c2a141fe3ebdce55da5e10149
We reused the processed voltage windows, pulse metadata, fixed recording-pair choices, source records, and retrieval code. All 16 input data files matched the parent manifest. We measured later sample variance outside one early shape, after removal of the later group mean.
- usesEnergy showed no clear AUC gain over waveform matching at 200–500 ms with early pair calibration in eight SEEG sessions sci:sha256:024118b36e043b5ac6e3f1c2b9af745d186ccdbab579eb3021931da9dae3bc16
We read its split of energy into template projection and residual terms when choosing the method. The new test measures variance across later pulses with a matched before control. It does not repeat the detection AUC comparison.
- usesdoi:10.18112/openneuro.ds004696.v1.0.1
Processed SEEG voltage derivatives and source metadata from OpenNeuro ds004696 version 1.0.1 were used.
- doi:10.1523/JNEUROSCI.2201-22.2023
- doi:10.1007/s10548-022-00928-7
- doi:10.1371/journal.pcbi.1011105
Cited by
5 publicationsPublic catalog entries on Sciscape.
- uses4–30 Hz SEEG variance remained greater after stimulation outside an early response plane in eight epilepsy patients
This report supplied the prior question about pulse variation outside a response shape. Its broadband result was known before this plan. Our test used frequency bands, all eligible pairs, and two early directions with matched controls.
- usesPaired after-to-before SEEG variance ratios were 1.51 times as large at 4–30 Hz as at 70–110 Hz in eight epilepsy patients
This report supplies the fixed 86 stimulation sites, all 886 eligible recording pairs, source metadata, hash pins, and the inherited five-pulse pair choice. We rebuilt the frequency inputs from all eight complete public source files.
- Later 20 to 100 ms SEEG variance outside a shape fitted from four pulses was 1.20 times the variance before pulses at 138 sites in five patients
[Legacy relation: reproduces] We tested its fitted-direction residual variance principle in ds004457 with five patients, four fit pulses, four distinct later test pulses, and a 20 to 100 ms window. The primary residual ratio was 1.201. This is a conceptual replication with different recording targets and site rules. It is not an exact protocol replication or a controlled comparison of ratios.
- usesGain fits with shifts up to 19.5 ms left 1.93 times the matched control variance in 59 to 460 ms SEEG at 86 selected sites in eight people
This study uses the fixed site choices, voltage windows, pulse order, source records, and retrieval recipe from this publication. It extends the fitted-template variance test with finite time shifts and matched controls.
- usesPaired after-to-before SEEG variance ratios were 1.51 times as large at 4–30 Hz as at 70–110 Hz in eight epilepsy patients
This report supplies the fixed 86 stimulation sites, all 886 eligible recording pairs, source metadata, hash pins, and the inherited five-pulse pair choice. We rebuilt the frequency inputs from all eight complete public source files.