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Gain fits with shifts up to 19.5 ms left 1.93 times the matched control variance in 59 to 460 ms SEEG at 86 selected sites in eight people

We tested a response model for a brain-computer interface that reads signals during stimulation. Public OpenNeuro ds004696 version 1.0.1 supplied SEEG data from eight people with epilepsy. The first five pulses defined a template at each of 86 fixed sites. We fitted a signed gain and a time shift to 610 later pulses. Shifts could extend 19.5 ms in either direction. The test window was 59.1 to 460.4 ms after a pulse. A matched control added each fitted response to its recorded pre-pulse activity and used the same fit. The equal-person residual variance ratio was 1.93. Its descriptive 95 percent person bootstrap interval was 1.56 to 2.44. All eight person ratios exceeded one. The shift search reduced observed residual variance by 17.2 percent and control variance by 8.9 percent. Wider shifts and a different template also left excess variance. This test assumes that pre-pulse activity is a useful background reference. It does not identify a neural cause or measure live BCI performance. The package preserves voltage windows, source hashes, pulse fits, two figures, and reproduction documentation; GPL scripts are excluded from the public package.

stereoelectroencephalography · electrical stimulation · brain-computer interface · response variability · time-shift model · matched control

Admitted 4 citing publications

References

5
  1. usesLater 20–500 ms SEEG variance outside a shape from five pulses was 2.11 times the variance before pulses at 86 selected sites in eight people sci:sha256:d7334af97e9ceb52d52f038db543c405d40b5dc0dfc1e79213b2dbb0abf242bb

    This study uses the fixed site choices, voltage windows, pulse order, source records, and retrieval recipe from this publication. It extends the fitted-template variance test with finite time shifts and matched controls.

  2. uses4–30 Hz SEEG variance remained greater after stimulation outside an early response plane in eight epilepsy patients sci:sha256:4e0a00e389aea5abca17ff3342ffafee0158c25370913bed80856b89e41ce7ae

    This study uses the response-plane and phase-slope test as a prior model check. It tests finite native-sample shifts and applies the same fit to constructed background controls.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analyzed voltage derivatives are from OpenNeuro ds004696 version 1.0.1.

  4. doi:10.1523/JNEUROSCI.2201-22.2023
  5. doi:10.1016/S1388-2457(01)00739-8

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