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A fixed shape gate did not establish higher 10 ms peak agreement in 140 selected SEEG pairs

We tested a fixed waveform-shape gate for single-pulse feedback after electrical brain stimulation in eight clinical SEEG sessions. Early calibration selected 140 recording pairs at 60 stimulation sites from OpenNeuro ds004696 v1.0.1. The gate accepted a later waveform when its correlation with the five-pulse calibration mean was at least 0.8. In a 20–500 ms window, a voltage peak agreed when it fell within 10 ms of the calibration peak. With equal patient weight, yield was 70.5%, and agreement among accepted outputs was 73.0%, compared with 69.5% without the gate. The paired change was 3.6 percentage points, with a descriptive 95% patient bootstrap interval from −1.4 to 8.2 points; the main test therefore did not establish higher agreement. The gate withheld agreeing readouts equal to 16.5% of all attempts. Mean acceptance of before-pulse controls was 0.45%. Some accepted waveforms had peak shifts above 450 ms despite high shape correlation. A fresh download reproduced all eight compact voltage files exactly. This exploratory retrospective test measures voltage-peak repeatability in selected clinical data. It does not test live brain-computer-interface performance.

SEEG · brain stimulation · single-pulse feedback · waveform correlation · peak timing · output yield · selective readout · reproducibility

Admitted 1 citing publication

References

5
  1. usesMeans of five pulses had higher 10 ms peak time agreement than single pulses in 140 selected SEEG pairs from eight patient sessions, within a 20–500 ms window sci:sha256:ee9468576896d327d9f9ef2d36d9e91a4cd1e76b429b995fe523bd304320eab2

    We used its exact voltage arrays, pulse roles, and selected cohort. We reproduced its single-pulse baseline and tested a fixed gate on each later pulse.

  2. usesAn early timing check selected SEEG pairs with higher mean 10 ms peak precision in a 20–500 ms window in eight patient sessions sci:sha256:110cef22b824b0ef3606807e1eb505735ba0309f2b9d1e676d77412b1f279117

    We used its early selection rule and its known limit on shape correlation and peak timing. This study measures individual later-pulse output yield and timing agreement.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    We used the exact voltage arrays, pulse roles, and selected cohort from OpenNeuro ds004696 v1.0.1.

  4. doi:10.1523/JNEUROSCI.2201-22.2023
  5. doi:10.1371/journal.pcbi.1011105

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