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The 95% patient interval included zero AUC gain from added post-seizure gamma rank weights of 0% to 50% in separate seizures from 29 SEEG patients under independent, exchangeable patient sampling

We tested whether gamma decrease after a seizure adds to onset gamma ranks. The public source was OpenNeuro ds004100 version 1.1.3. The main sample had 29 patients and 472 adjacent bipolar pairs on 62 shafts. We selected an added rank weight from 0% to 50% on run 01 of each patient and tested it on run 02. Mean test AUC changed from 0.9023 to 0.9045. The mean gain was 0.0023. The 95% patient bootstrap interval was -0.0179 to 0.0232. It included zero. Its population interpretation requires independent, exchangeable patients. The exact sign test gave p = 0.8281 under symmetric null patient effects. The rule selected onset alone in 21 patients. All ten planned descriptive checks are reported. This exploratory result did not establish an added mean gain under the tested rule. It did not establish equivalent scores or absence of useful post-seizure information. Separate checks matched 320 public signal ranges, 197 metadata files, and all 279,180 stored gamma power values. A fresh numerical run matched all 16 analysis output files. The package preserves the unchanged parent power data, code, source pins, candidate tables, uncertainty draws, and repeat instructions. The result concerns clinical SOZ marks in a reused cohort. It does not establish surgical benefit.

stereoelectroencephalography · epilepsy · seizure onset zone · gamma power · rank AUC · separate-seizure validation · patient bootstrap

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References

4
  1. usesGamma recovery did not improve mean SOZ rank loss in 29 ds004100 SEEG patients under a fixed linear model sci:sha256:dea4caaf10f762ac2f75085fd938456ec7e9bbdf4daa5719d734cc4fc1257ed0

    We read this related report after our analysis and source checks were complete. It supplied context for the discussion of added gamma features on the same data. It did not inform the locked plan, scores, selection rule, or results.

  2. usesChoice among 12 scores gave a mean AUC gain of 0.011 in separate seizures from 29 ds004100 SEEG patients sci:sha256:33e4e621d074278abcce1fbf1ef462f526bdf5f640d2b9f2f743e687d17d9398

    We read this report before the local plan. Its score selection across separate seizures informed our fit and test design. The post-seizure parent supplied the actual input files.

  3. usesGamma decrease 10–30 seconds after seizure end gave mean within-shaft AUC 0.790 for SOZ marks in 29 ds004100 SEEG patients sci:sha256:99be67b99ddbb5d8f4a313e37c0796d3d1720b9c5256eb23bdc178856757d497

    This publication supplied all 64 power files, source marks, headers, fixed object versions, range hashes, extraction code, and a raw signal period. We preserved all 495 files unchanged and used its fixed support for the new rank test.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source recordings and clinical marks from OpenNeuro ds004100 version 1.1.3.

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