Schizophrenia and control groups have a 12.82 ms delay field contrast in the same 22 CNP task schedules.
In 241 screened sessions from the UCLA Consortium for Neuropsychiatric Phenomics (CNP) dataset, schizophrenia and control groups shared 22 task schedules in 121 sessions. The schedule-specific weighted coefficient for the difference in the recorded delay-field contrast was 12.818055425854965 ms. This was 6.087073943998796 ms below the pooled contrast in all screened schizophrenia and control sessions (18.90512936985376 ms). The coefficient is a difference in recorded fields; it does not identify delivered acoustic stop timing or a causal effect of diagnosis. Participant-resampling percentiles were 1.1155673639507817 to 24.503152049746422 ms, while whole-schedule-resampling percentiles were -3.6651204430694984 to 33.70433691289282 ms and included zero. These ranges use different resampling units and have no established population coverage. Age, gender, scanner identifier, medication, and performance-based selection remain limitations.
stop-signal task · schizophrenia · task schedules · reaction time · delay fields · CNP · OpenNeuro · bootstrap · ordinary least squares · measurement limitations
References
6- usesThe mean SSRT difference between schizophrenia and control groups changes by 18.91 ms between two delay fields in 166 selected CNP sessions. sci:sha256:f2de8227103541aa79bc15f834b132c181de9b75fe3f45f5097e02ecb6d8b029
The primary screen and pooled 18.905129369853753 ms contrast defined the comparison. We calculated a new coefficient for common schedules in the same participant data.
- usesIndependent calculations reproduce 266 CNP SSRT results and a 248-session screen sci:sha256:6abd7a0e35743e8c322c741b16f554db575bd753352c5e7ba40ed4c8fdd77f2b
The verified 272 source files, pinned source manifest, and 266 session outputs supplied the data and reference values for this calculation. We wrote new analysis code.
- usesAll 140 patient runs have a task schedule that also occurs in control runs in ds000030 1.0.0. sci:sha256:5bb35f38a1263e76b5273023cf3ce7b9f7dfc1df71d6d520527b411073975b41
The task schedule definition and diagnosis overlap result motivated the coefficient for common schedules. We calculated schedule membership and counts again from the source tables.
- usesdoi:10.18112/openneuro.ds000030.v1.0.0
The analyzed participant and stop-signal event tables are from OpenNeuro ds000030 version 1.0.0; the source manifest records their exact object versions and SHA256 hashes.
- supportsdoi:10.1038/sdata.2016.110
This report describes the CNP task design, including its 96 GO and 32 STOP trials per session.
- supportsdoi:10.7554/eLife.46323
This consensus guide supplies the cited recommendation of at least 50 STOP trials for standard group SSRT estimates under favorable conditions.
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesThe 12.82 ms delay field difference is in the 95% label reference range for 121 CNP sessions.
Used its pinned public tables, delay field outcome, task schedule rule, and session values. These inputs enabled raw-data checks and the primary label reference.
- usesA schedule and scanner model gives a 16.41 ms delay field difference in 88 selected CNP sessions.
This report supplied the task schedule definition, the schedule-only comparison, and the open comparison with schedule and scanner cells.