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An update from unfiltered STE marks at strength 0.5 increased mean MNI map error in later 30-minute samples from 18 SEEG records

We tested whether current STE detector marks can improve an earlier MNI detector channel map. We used the first hour of one public SEEG sleep record from each of 18 patients in OpenNeuro ds005398 version 1.1.3. The fixed update had strength 0.5 and smoothing of one count per channel. It used the first 30 minutes for calibration and the next 30 minutes for the test. The mean squared Hellinger error rose from 0.020703 for the earlier MNI map to 0.025754 for the update. Mean gain was -0.005051, with a patient bootstrap 95% interval of [-0.008261, -0.001918]. The update had more error in 12 of 18 patients. It had much less error than raw STE, which shows why the earlier MNI map is a necessary comparison. A fixed source score filter reversed the mean gain. That check is descriptive and has no multiple-test adjustment. This result concerns retrospective agreement with released MNI marks. MNI marks are not clinical ground truth. The package has all used source inputs, fixed versions, hashes, code, patient scores, figures, independent checks, and an offline reproduction procedure.

high-frequency oscillations · stereo-EEG · SEEG · detector transfer · Hellinger distance · OpenNeuro

Admitted 9 citing publications

References

4
  1. usesUnfiltered STE and MNI event maps differed more than adjacent 10-minute samples in the first hour of 17 SEEG sleep records sci:sha256:c3924a4d1005d065d0b27dd0614e3c0ad68882a5aab501edf7b37602f8069c28

    The prior publication supplied exact source files, source hashes, fixed object versions, eligibility rules, counts, and the audit. We used them to build and check the new fixed update test. The two analyses use the same SEEG cohort.

  2. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    The publication analyzes released event files and metadata from this exact dataset version; its version-pinned metadata records the DOI and CC0 license.

  3. doi:10.1016/j.clinph.2023.07.012
  4. doi:10.1111/epi.18545

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