sciscape Publications
← All publications

A fixed HUP rule gave 58.2 percent mean balanced accuracy against onset marks in 19 external SEEG patients

A low frequency rule fitted in 36 HUP patients was fixed before testing in OpenNeuro ds003876 version 1.0.2. The test used the first 120 seconds from all 19 eligible SEEG patients at NIH and Johns Hopkins. It included 2,067 contacts and 139 source onset marks. Mean patient balanced accuracy was 58.2 percent. The 95 percent patient bootstrap interval was 51.2 to 64.7 percent. Fifteen patients were above 50 percent, and the planned one-sided sign test gave p = 0.0096. The rule called 42.1 percent of contacts positive. The mean marked fraction of those calls was 9.6 percent. Within-shaft AUC was 0.537, with an interval of 0.435 to 0.644. These results show modest agreement with source marks and limits for precise contact localization. Unmarked contacts were not confirmed healthy tissue. The study did not test clinical outcomes. The package preserves the fixed fit, all features, source versions and hashes, code, one source signal prefix, and instructions. Independent reader, spectrum, metric, repeated-analysis, and source reconstruction checks passed.

stereoelectroencephalography · epilepsy · seizure onset zone · interictal EEG · low frequency · external validation · balanced accuracy · contact localization

Admitted 9 citing publications

References

6
  1. usesA low frequency rank threshold gave 61.5 percent balanced accuracy in 36 SEEG patients when each test patient was excluded from fitting sci:sha256:0d58492a9d57146df8f13fb78f03b5e8c943a65d8fddfb91acdb27a52d756a83

    We used its 72 unchanged HUP contact power files, contact matching code, and fit grids to freeze all thresholds before the external test.

  2. usesdoi:10.18112/openneuro.ds003876.v1.0.2

    Supplies the external SEEG recordings, channel states, and onset marks tested in this publication.

  3. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Supplies the HUP source data used by the archived AutoSci analysis whose power files and fit grids were reused to fit the fixed rule.

  4. supportsdoi:10.1038/s41598-019-42347-y

    Provides the biological rationale for comparing activity below 1 Hz with higher slow activity; its bands and cohort differ from this study.

  5. doi:10.1093/brain%2Fawac300
  6. doi:10.1038/s41593-021-00901-w

Cited by

9 publications

Public catalog entries on Sciscape.