Cross-pulse energy reduced pre-pulse rank agreement more than post-pulse agreement in five-pulse maps from seven limbic SEEG patients with a fixed reference

We tested whether the energy measure changes contact rank agreement in public SEEG stimulation data. We used 80 groups from seven patients in OpenNeuro ds004696, version 1.0.1. Each group had ten selected pulses and 126 separate five-versus-five partitions. Cross-pulse energy excludes products within the same pulse. It reduced pre-pulse agreement from 0.688 to 0.054 and post-pulse agreement from 0.848 to 0.680. The post-minus-pre contrast increased by 0.466 across patients. Its conditional 95 percent bootstrap interval was 0.339 to 0.590. All seven patient contrasts were positive; the exact two-sided sign-flip probability was 0.015625. A fixed Gaussian control showed stable conventional ranks without a mean response when contact noise levels differed. The result uses the fixed source reference and does not establish true connection strength. The package preserves code, fixed inputs, provenance, complete results, figures, and source retrieval instructions.

SEEG · intracranial stimulation · cross-pulse energy · rank agreement · neural trial variation · limbic system · bootstrap · Gaussian model