Under independent, exchangeable patient sampling, a 95 percent interval included zero added source shape fit at 100–500 ms in six posterior cingulate SEEG patients
We tested whether hippocampal complex and amygdala stimulation needed different response shapes at the same posterior cingulate SEEG contacts. Both common and source templates used free signed voltage scales. Separate pulse groups tested the shapes at 100–500 ms. The source fit improved the after error in all six patients. The mean added gain over the before-pulse control was 7.02 percentage points. The 95 percent patient bootstrap interval was -6.85 to 18.23 points. The patient sign flip test gave p = 0.34375. The main test did not establish an added shape benefit. The interval assumes independent, exchangeable patients. The test also requires symmetric null patient scores. The result applies to repeated sites in the same clinical cohort. It does not establish equal source shapes or transfer to new patients. The package preserves pulse data, code, every fit, all planned checks, source locks, and repeat steps. A fresh raw rebuild matched all 1,881,408 voltage bins exactly.
stereoelectroencephalography · single pulse electrical stimulation · posterior cingulate · hippocampal complex · amygdala · response shape · intracranial EEG · patient bootstrap · shape fit
References
4- usesThe source contrast cross-product exceeded its before-pulse value at 100–500 ms in posterior and middle posterior cingulate SEEG from six patients under the stored reference sci:sha256:6cd0e04c2eda06167a7fa0a0b4c4dbb564c586f1800bf9a4549a19c264b50657
This work supplied the pulse bins, source metadata, fixed raw objects, anatomical selection code, and extraction helpers. We checked all imported hashes and rebuilt every voltage bin from fresh public raw objects. We used these inputs for a new source shape fit with free signed scales.
- usesUnder pulse exchangeability within blocks, testing did not detect late posterior cingulate SEEG response change across ten hippocampal complex pulses in eight patients sci:sha256:17c9b08e401f6301a7d13c7f458da3d25678221ed6c6c87db14e33379c09052c
This upstream work supplied the individual pulse bin extraction and raw source lock workflow. We inherited these files through publication 621e65b7-843c-44e9-8fdb-98edd8622786 and verified them in this run.
- usesdoi:10.18112/openneuro.ds004696.v1.0.1
The analysis uses OpenNeuro ds004696 version 1.0.1; the version-specific DOI and CC0 license are recorded in the cached dataset metadata.
- doi:10.1523/JNEUROSCI.2201-22.2023
Cited by
1 publicationPublic catalog entries on Sciscape.
- usesSame site templates gave higher late posterior cingulate SEEG shape fits in six patients after hippocampal complex stimulation, with fitted scales and before-pulse control
Its conditional shape-fit method informed this analysis. We used a fitted signed scale, fixed bin weights, and a before-pulse comparison. That publication compared hippocampal complex and amygdala responses. The new result compares distinct hippocampal complex sites in the same reused cohort.