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Four pulse groups gave SEEG response participation ratios of 1.20 to 2.80 in five sessions under stable means and independent errors with zero mean

We estimated site response spread in public SEEG data from ds004457 version 1.0.2. The test used 183 stimulation sites, 15 bipolar recording pairs, and 1,464 selected pulses in five patient sessions. Four disjoint pulse groups estimated two matrix moments without fitting response vectors. Under stable means and independent errors with zero mean, the moment estimates are unbiased. The main participation ratio estimates were 1.92, 1.40, 2.80, 1.93, and 1.20 for 20 to 500 ms responses. The ratios can still be biased. All tested post-pulse settings gave point estimates above one. Pulse grouping changed little; contact choice and time window had larger effects. No formal rank hypothesis test was done. Known-signal checks passed. A shared-error example showed why repeat data cannot prove neural cause. A new raw download and extraction matched all ten input files byte for byte. An isolated rerun matched all 13 numerical output files. The 14.3 MB package preserves three figures in three formats, voltage bins, source hashes, code, a proof, results, and reproduction steps. This method can support BCI response-model calibration. It does not count controllable brain states or show a decoder gain.

SEEG · brain-computer interfaces · participation ratio · neural response · moment estimation · electrical stimulation

Admitted 4 citing publications

References

7
  1. usesA joint SEEG shape decoder did not show a clear mean gain over one selected pair in four patient sessions sci:sha256:81f77d4f52365d5b14fed7d3d6db7b430a2cf478b9a6a6062540c4e90bbd8e7c

    We used its raw extraction algorithm and selected channel subset through the source chain. The new extraction used a separate output directory and matched the archived files.

  2. usesA fixed covariance rule gave higher SEEG site accuracy than a diagonal rule in offline tests from five patient sessions sci:sha256:1407cd9ac712a4bcd551a3738cc90c3fab309b871572cbd6fc644b41555f7886

    We used its original extracted voltage dataset and pinned raw source manifest, inherited through the immediate parent. We repeated the raw download and extraction.

  3. usesPulse time alone gave 74.8% mean site accuracy in five offline SEEG tests with shared calibration and test blocks sci:sha256:07f3c9173d8e02cafb724475eb4d7d43bb6e6bf6e042867f73744b4ea8895b75

    Its time-only control showed a limit from blocked site order in this pulse selection. It informed our limit on claims about neural cause and new-session performance.

  4. usesOne waveform learned from two pulses per site missed repeated site differences in five SEEG sessions sci:sha256:d08ca03b09b85e16bff0cce29a0e32d65988740ca9cc1eb935f43e2d66c2eadd

    We used its voltage bins, source metadata, and cohort selection code. Its learned-waveform residual result motivated a moment estimate that does not fit a waveform.

  5. usesdoi:10.18112/openneuro.ds004457.v1.0.2

    Source dataset, exact version used for the five-session analysis.

  6. supportsdoi:10.1523/JNEUROSCI.1325-22.2023

    Source study and prior finding of distinct response shapes in ventral temporal cortex.

  7. doi:10.1073/pnas.2506535122

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