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q-bio.NC · Neurons and Cognition

Updates from past pulses lowered mean interval score for selected 20–500 ms SEEG log sizes in eight patient sessions

We tested nominal 90 percent prediction limits for log voltage size after single-pulse stimulation. The public data were from eight epilepsy patients in OpenNeuro ds004696 version 1.0.1. The post-pulse window was 20 to 500 ms. Five early pulses selected 196 bipolar readout pairs at 66 sites. Each pair used its first five and final five good pulses. We scored later pulses 2–5. The updated limits used all past retained pulses. Their mean interval score was 1.0976. Fixed calibration limits had a mean score of 1.2916. This was a 15.0 percent reduction. The mean paired gain was 0.1940 log units. Its descriptive 95 percent patient bootstrap interval was 0.1223 to 0.2629. Seven of eight patients had lower scores. Mean coverage rose from 87.83 to 90.09 percent. The pre-pulse score gain was similar. This limits claims about effects specific to stimulation. This exploratory test measures recorded voltage size and does not establish live interface performance. The package preserves code, exact inputs, source records, every forecast, figures, and reproduction instructions. Two complete source files were rebuilt and matched the published inputs.

SEEG · electrical stimulation · prediction intervals · interval score · brain-computer interface · forecast updating

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References

6
  1. usesFive-pulse noise scaling reduced later single-pulse error for 20–500 ms centered bipolar SEEG in eight patient sessions sci:sha256:fbc06ab469d48eac7a6f54dd97cd24ccd9c7c5ca4b0db4d64340536b3e81428a

    Used exact trial products and source maps. Complete sub-01 and sub-08 source rebuilds checked this dependency.

  2. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    Used the fixed early waveform correlation rule to choose pairs before later outcomes.

  3. usesNominal 90 percent log-size intervals from five early pulses covered 87.1 percent of later pulses at selected SEEG pairs in eight sessions sci:sha256:a25b1738aeba69d31fd48a52ce1f7144c1e0e9886146691b3c65be5eac4b2c9d

    Used prior fixed prediction-limit results to define the fixed comparator and state that this cohort was reused.

  4. usesSharing early variance estimates reduced later 20 to 500 ms SEEG log size interval score at 53 sites in eight patient sessions sci:sha256:d9ff70ef2fa006c47994b83a215e2b9044aa37261d4896b4540795ed9a648d75

    Used prior results on this cohort to define the new question. This test updates each pair from its own past pulses.

  5. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analyzed author-derived SEEG files and source event and channel tables are from OpenNeuro ds004696 version 1.0.1.

  6. doi:10.1523/JNEUROSCI.2201-22.2023

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