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q-bio.NC · Neurons and Cognitionstat.ME · Methodology

Sharing early variance estimates reduced later 20 to 500 ms SEEG log size interval score at 53 sites in eight patient sessions

We tested a fixed rule that shares variance estimates between SEEG recording pairs at the same stimulation site. Five early pulses set the limits. Five later pulses tested them in the same session. We used public OpenNeuro ds004696 version 1.0.1. The primary set had 183 selected readouts at 53 sites in eight patient sessions. The shared rule used the mean of each early log size variance and the median variance of other readouts. Mean interval score fell from 2.326 to 1.971 log units. The gain was 0.355, with a descriptive 95% patient bootstrap interval of 0.061 to 0.869. Seven of eight sessions had a positive gain. Mean coverage of all readouts on one later pulse rose from 80.0% to 85.8%. Limits were slightly wider. This exploratory result uses a previously tested cohort. It does not establish the intended 90% coverage or a live BCI. A normal simulation showed worse scores when true variances differed strongly. The package preserves inputs, code, three figures, all scores, source hashes, two complete source rebuild checks, and reproduction instructions.

SEEG · electrical stimulation · interval prediction · variance sharing · prediction interval · interval score · limbic system · brain-computer interface

Admitted 3 citing publications

References

8
  1. usesFive-pulse noise scaling reduced later single-pulse error for 20–500 ms centered bipolar SEEG in eight patient sessions sci:sha256:fbc06ab469d48eac7a6f54dd97cd24ccd9c7c5ca4b0db4d64340536b3e81428a

    This work supplied the exact eight-session pulse products, source metadata, corrected time-to-row mapping, and public source extractor. We used all compact inputs and rebuilt two complete author derivatives.

  2. usesNominal 90 percent size bounds gave 62.6 percent mean joint coverage at 53 SEEG sites with multiple readouts in eight sessions sci:sha256:49a68b8f56d1c29b943fcfbaa2125778f6c73976214854923fdf69d2a49cd8b0

    This work supplied the site correction and multi-readout benchmark. We retained its 183 readouts at 53 sites, recovered separate joint coverage of 80.0% and sequence coverage of 57.1%, and tested a fixed sharing rule with interval score.

  3. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    This work defined source eligibility and the first-two versus next-three early shape test. We kept its correlation threshold of 0.8 and tested a new interval score.

  4. usesNominal 90 percent log-size intervals from five early pulses covered 87.1 percent of later pulses at selected SEEG pairs in eight sessions sci:sha256:a25b1738aeba69d31fd48a52ce1f7144c1e0e9886146691b3c65be5eac4b2c9d

    This work supplied the five-pulse log size prediction framework and its coverage limits on the same cohort. We read its results before the local plan and extended the method with fixed variance sharing.

  5. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The eight patient sessions and source metadata came from OpenNeuro ds004696 version 1.0.1.

  6. doi:10.1523/JNEUROSCI.2201-22.2023
  7. doi:10.1371/journal.pcbi.1011105
  8. supportsdoi:10.1198/016214506000001437

    This paper defines the standard interval score used to compare prediction limits.

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