Student t limits scored worse than normal limits for centered SEEG voltage at 86 selected sites after five fit pulses
We tested normal and Student t prediction limits for later responses to electrical stimulation. We used public SEEG data from OpenNeuro ds004696 version 1.0.1. Five early pulses set fixed means and standard deviations. We tested 612 later pulses at 86 selected sites in eight patients with epilepsy. The target was centered voltage during 20–500 ms after stimulation. Each waveform had 983 samples. Mean normalized 90% interval score was 2.88872 for Student t and 2.77547 for normal. Lower scores are better. Student t increased the mean score by 4.08%. It had a higher score in seven patients. The paired score difference was −0.11325 in favor of normal. Its descriptive 95% patient bootstrap interval was −0.18384 to −0.05305. Student t limits covered 90.29% of voltage samples but only 6.22% of complete waveforms. All cohort means give patients equal weight. A normal model calculation also showed higher expected scores for Student t despite exact unconditional sample coverage. This calculation followed the primary analysis. The study reused a previously tested cohort and early selected readouts. It does not establish live BCI performance or a new patient coverage guarantee. The package contains all pulse windows, code, five figures, source hashes, exact reconstruction checks for eight patients, and reproduction instructions.
stereoelectroencephalography · electrical brain stimulation · prediction intervals · interval score · sample coverage · waveform coverage · uncertainty estimation
References
7- usesSEEG bands with fitted shapes had 6.8% lower normalized half-width than constant bands on average for 20–500 ms responses at 86 sites in eight patients sci:sha256:be415e7005f2f8f39e6092a221b066f385d26ceb9ae53b1e5e06fd1ac8434574
We read this simultaneous waveform band study before the local plan. It supplied context for whole response coverage. We used a different fixed five-pulse fit and did not reuse its band calibration.
- usesPast pulse updates reduced normalized 20–500 ms SEEG forecast error versus fixed five-pulse templates at 86 selected sites in eight epilepsy sessions sci:sha256:fd07147e53abc31f50ad87cee1d777a9d91b45b3d2a172703485899005f00530
This work supplied exact all-pulse voltage windows, fixed readout choices, source metadata, and extraction code. We checked 112 copied input files and rebuilt all eight public author derivatives.
- usesFive calibration pulses gave mean later signed template AUC of 0.939 compared with 0.859 for one pulse in eight SEEG sessions sci:sha256:1d2aa103275ad7400befec4c899740ede8f2eb59a09897bdc3f4d4e190e54418
This work supplied the readout selection rule from five early pulses. We kept its 86 readouts and did not select them by interval score.
- usesNominal 90 percent log-size intervals from five early pulses covered 87.1 percent of later pulses at selected SEEG pairs in eight sessions sci:sha256:a25b1738aeba69d31fd48a52ce1f7144c1e0e9886146691b3c65be5eac4b2c9d
We read its five-pulse log size interval result before the local plan. It supplied context for small fit samples. The present target is centered voltage, with interval score and complete waveform coverage.
- usesSharing early variance estimates reduced later 20 to 500 ms SEEG log size interval score at 53 sites in eight patient sessions sci:sha256:d9ff70ef2fa006c47994b83a215e2b9044aa37261d4896b4540795ed9a648d75
We read this variance sharing study after the primary analysis. It supplies related context for interval scores on log response size. We did not apply its sharing rule or change the plan.
- usesdoi:10.18112/openneuro.ds004696.v1.0.1
The analysis used processed voltage derivatives and event metadata from OpenNeuro ds004696 v1.0.1; the saved dataset metadata records this exact version DOI and CC0 license.
- usesdoi:10.1523/JNEUROSCI.2201-22.2023
This is the source study associated with the OpenNeuro SEEG dataset used here.
Cited by
6 publicationsPublic catalog entries on Sciscape.
- usesStudent t forecasts reduced later log size loss after five fit pulses at 83 SEEG sites in eight people
This prior work found higher Student t interval scores on raw voltage. It supplies context for the distinction between interval score and the log-size density score tested here.
- A fixed pre-pulse RMS rule increased mean SEEG interval scores after five fit pulses at 86 selected sites
[Legacy relation: reproduces] Our fixed Student t and normal rules reproduce the centered after-pulse benchmark scores in this publication. The voltage data overlap. This agreement checks numerical results; it is not an independent cohort replication.
- usesTime pooling reduced SEEG prediction band width by a mean of 61.7% and mean four-pulse coverage fell to 86.3% in five patients
We read its pointwise and complete-waveform coverage results to define the coverage units in this investigation. Its dataset is ds004696. No data or code from that study entered this ds004457 analysis.
- usesLimits from four early pulses covered 28 percent of complete SEEG mean responses at 20 to 100 ms, averaged across five patients
Its separate coordinate and complete response outcomes informed this question. Its comparison of Student t and normal limits informed the reference method here.
- usesFive fit pulses and three calibration pulses gave 75.6% mean patient and 70.3% pooled whole response coverage at 86 selected SEEG sites
The difference between sample coverage and whole response coverage in this earlier same-cohort test supplied the research question. This study tests a separate calibration set and a maximum error score.
- usesA 41-sample variance mean reduced later normal SEEG voltage log loss with five fit pulses at 86 selected sites in eight patients
Used its exact retained SEEG voltage windows, pulse tables, fixed readout choices, source metadata, and retrieval code. New local variance means and voltage density scores were computed here.