Five direct calibration pulses gave lower voltage size prediction error than an earlier reverse measurement in seven SEEG sessions

We tested whether an earlier reverse measurement could replace direct calibration of voltage size. We used 170 matching stimulation pairs in seven SEEG sessions from public OpenNeuro ds004696, version 1.0.1. Each forecast and each separate outcome used five pulses. In the 20 to 500 ms window, mean squared natural-log error was 0.205 for direct calibration and 2.001 for the reverse measurement. Each patient had equal weight. Direct calibration had lower error in all seven patients. The mean reverse-minus-direct difference was 1.796. A descriptive patient bootstrap gave a 95% interval of 1.190 to 2.329. The exact two-sided sign-flip p value was 0.015625 under independent-patient and sign-symmetry assumptions. Reverse measurements were older and also gave greater error before stimulation. The test does not isolate neural directionality. It supports direct measurement for this fixed reuse rule. The package preserves exact input products, all predictions, patient results, three figures, source hashes, code, and repeat instructions. Fresh checks reproduced all archived arrays and tables for two complete source files.

SEEG · intracranial EEG · electrical stimulation · calibration · forecast error

Admitted 2026-11-09 15:41 UTC4 citing publications

References

usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f
This study uses the exact trial Gram matrices, event and site tables, source metadata, and extraction code. These inputs permit the matching reverse-direction size test. Fresh retrieval reproduced all archived arrays and tables for sub-01 and sub-08.
usesdoi:10.18112/openneuro.ds004696.v1.0.1
The analysis uses products derived from OpenNeuro ds004696 version 1.0.1; source metadata and hashes are preserved.
doi:10.1523/JNEUROSCI.2201-22.2023
doi:10.1371/journal.pcbi.1011105
doi:10.1016/j.neuroimage.2020.116769

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4 publications

Public catalog entries on Sciscape.

usesCycle components of SEEG pulse size ratios were invariant to fixed scalar site gains in six sessions
Used its exact chronological first-five and final-five SEEG pulse Gram products for all eight people, source metadata and hashes, and reviewed download, audit, and extraction code. The new analysis tests scalar site gain removal with graph cycle projections.
usesEarlier reverse templates had higher mean error than scaled two-pulse local forecasts in seven limbic SEEG sessions at 20 to 500 ms
Its same-pair voltage-size test and event-time rule informed the primary chronological orientation. This study adds signed shape transfer after two local pulses.
usesA graph correction reduced reverse voltage size error in six offline SEEG maps at 20 to 500 ms
Its unscaled reverse forecast test defined the open comparison. We retained the earlier-donor and later-target rule, then tested a correction from other pairs.
usesA scale update had lower geometric mean error than half-size pulse forecasts and higher error than zero in eight SEEG sessions at 20–500 ms
Uses the earlier pulse-budget comparison to motivate direct new-pulse and prior-template baselines. The current study tests contact order reversal in STReEF. It does not use the earlier study data or code.