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Selected beta imaginary coherency graphs had positive signed scores in the next minute for all 19 SEEG patients

We tested whether beta spectral phase signs persisted in the next minute. We used public SEEG from OpenNeuro ds003876, version 1.0.2. A fixed sample had 19 patients with epilepsy. We selected the top 10 percent of eligible imaginary coherency edges in one minute, then tested their signs in the next minute. The primary analysis used the recorded reference and 13 to 29.5 Hz bins. All 19 patient signed scores were positive. Their mean was 0.04850. The 95 percent patient bootstrap interval was 0.02284 to 0.08200. The exact two-sided sign test gave p = 0.000003815 under independent patient signs with equal positive and negative probabilities. The mean patient ratio of test signed score to training absolute score was 0.2484. Mean selected-edge Dice overlap was 0.2835. Positive signed scores thus coexisted with changes in graph membership. We rebuilt all 4,222,800 Fourier coefficients from pinned public source ranges. A full analysis of the rebuilt inputs reproduced four result files byte for byte. The package preserves code, inputs, patient and edge results, figures, source hashes, and reproduction instructions. Earlier graph results informed this question. This is a new analysis of the same patients. Adjacent minutes, artifacts, and reference mixing limit the result. The score does not show information flow or causal neural connections.

stereoelectroencephalography · imaginary coherency · beta oscillations · spectral phase · sign persistence · epilepsy · signal analysis

Admitted 9 citing publications

References

6
  1. usesTop 10 percent beta imaginary coherency graphs had mean Dice agreement of 0.36 across recorded and common average references in 19 SEEG records sci:sha256:cabd47f37ca4f299ef3f9af674f8bb00bcaea94acc9e06355d6f7a282596a680

    We used its fixed 19-patient sample, beta Fourier inputs, eligible pair order, and source records. Its graph overlap results informed this new next-minute signed-score question.

  2. usesReference choice reduced mean 80 to 150 Hz rank agreement more than time change in 19 public SEEG records sci:sha256:16d6a5e5126b007f6f6be4f042d829df32ccd751f41bcfda4c9b9a3f5a80fce2

    The inherited sample selection, source metadata, range identities, and EDF helper originated in this work. We preserved its selection code and adapted its EDF helper through the beta graph parent. We did not use its high gamma results.

  3. usesdoi:10.18112/openneuro.ds003876.v1.0.2

    Source dataset used for the fixed sample of 19 patients and source reconstructions; exact version 1.0.2 is recorded in the saved dataset metadata.

  4. doi:10.1016/j.clinph.2004.04.029
  5. doi:10.1038/s41593-021-00901-w
  6. doi:10.1101/2021.10.15.464594

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