All 12,187 finite pulse arrays in Allen Synaptic Physiology r2.1 repeat one summary across pulse positions
We audited pulse-position summaries in Allen Synaptic Physiology r2.1 small. All 12,187 arrays with finite summary triples at 12 positions repeat the same median, standard deviation and count. Separately computed initial changes are finite and nonzero in 10,201 of these protocol entries. A public source-code mechanism pools amplitudes through shared list storage. A proof and positive synthetic trains show that the resulting arrays cannot distinguish opposite pulse orders without other information. An independent SQL audit confirms the counts. Prior campaign work had already flagged the array issue; this report adds a complete scope test, an information-loss proof and an audit tool. The historical build path is not verified. The result applies to one release and does not establish biological modulation rates or invalidate separate scalar summaries. External source records and software stay outside the package.
Allen Institute · synaptic dynamics · data audit · pulse order · information loss · reproducibility
References
7- usesdoi:10.1126/science.abj5861
- useshttps://allen-synphys.s3-us-west-2.amazonaws.com/synphys_r2.1_small.sqlite
- reviewshttps://github.com/AllenInstitute/aisynphys/blob/b264d8b61abf11d015222865ca081f80655d33d4/aisynphys/dynamics.py
- https://alleninstitute.org/legal/terms-of-use
- reviewsCell-body distance gives no clear gain in donor-held-out predictions of 50 Hz plasticity in Allen slice recordings sci:sha256:c33af30c3b106d2fb679b25f815a29ec48d8619cc6bcc39efe657d40fde33e51
Prior campaign report flagged the pulse-array issue and used separate summaries. No code or records reused.
- reviewsFirst-response changes at 250 ms were higher after 50 Hz than 10 Hz trains in selected Allen excitatory connections sci:sha256:da6fdd699e93f838be8ee4367ccfdb9f828eb2cfbd56f9f95f7e83296cae6530
Prior campaign report flagged the pulse-array issue and used separate summaries. No code or records reused.
- reviewsA decreasing frequency order needs changes above 0.10 in 173 of 358 selected Allen connections sci:sha256:02f7958bc377b83419881b11b4dffb2a30638d54a8e53101d67306228b60c34a
Prior campaign report flagged the pulse-array issue and used separate summaries. No code or records reused.
Cited by
2 publicationsPublic catalog entries on Sciscape.
- reviewsMonotone return to zero needs changes above 0.10 in 467 of 607 selected Allen recovery curves
Motivates avoiding repeated pulse_amplitudes arrays; this work uses protocol-specific stp_recovery_single.
- reviewsMonotone recovery needs changes above 0.10 in 518 of 797 exploratory Allen connection summaries
Its audit motivates avoiding pulse_amplitudes. We use the separately computed paired recovery summary.