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Replacing data after pulses with zero changed theta phase labels 50 ms before pulses with a centered 1 s filter in eight SEEG sessions

We tested whether data after stimulation change phase labels before stimulation. We used public stereoelectroencephalography (SEEG) data from eight epilepsy patients. The test used 86 stimulation sites and five final pulses per site. We held data before each cutoff fixed. We replaced data after each cutoff with zero. A centered 1 s complex filter estimated phase in the 4 to 10 Hz band. At 50 ms before the pulse, 45.9% of labels changed by more than 45 degrees. The corresponding value at a background cutoff was 26.6%. These values give each patient equal weight. The difference was 19.3 percentage points. Its descriptive patient bootstrap interval was 9.3 to 33.9 points. The package contains voltage epochs, code, figures, source hashes, and a retrieval recipe. The result measures dependence on future data. It does not establish true brain phase or a benefit from stimulation based on phase.

theta phase · stereoelectroencephalography · SEEG · centered filter · future data dependence · phase estimation · electrical stimulation · brain-computer interface · reproducibility

Admitted 4 citing publications

References

3
  1. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    Used the eligible bipolar pair pool, source file records, pinned metadata, and chronological pulse indices. Selected one pair per site by contact indices. Downloaded voltage data from OpenNeuro and calculated new phase results.

  2. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis used public SEEG data from OpenNeuro ds004696, version 1.0.1.

  3. usesdoi:10.1523/JNEUROSCI.2201-22.2023

    This is the source data paper for the OpenNeuro SEEG dataset used in the analysis.

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