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After 10 ms repair, later voltage changed centered 1 s theta phase labels 50 ms before pulses in eight SEEG sessions

We tested whether a short pulse repair removes dependence on later voltage from a phase label before the pulse. We used public stereoelectroencephalography (SEEG) data from eight epilepsy patients in OpenNeuro ds004696, version 1.0.1. The main test used 86 sites and five final pulses per site. A centered 1 s complex filter measured phase in the nominal 4 to 10 Hz band. The label was 50 ms before each cut. Both traces had the same past and the same repair for the first 10 ms after the cut. This repair used only the past. We replaced later voltage with reflected past voltage in one trace. Mean absolute phase change was 53.31 degrees at pulses and 32.79 degrees at background cuts. The paired difference was 20.52 degrees. Its descriptive 95% patient bootstrap interval was 9.72 to 34.14 degrees. All eight patient differences were positive. Replacement of the 10 to 100 ms interval alone also gave a large change. The 100 to 450 ms interval gave smaller changes and no clear pulse excess. A separate check with the past mean as the initial repair gave a similar main contrast. The package preserves lossless voltage epochs, code, two figures, source hashes, all main trial results, and retrieval instructions. This is a conceptual replication and a method extension. It measures filter dependence on later input. It does not measure true neural phase or a live brain interface benefit.

SEEG · stereoelectroencephalography · theta phase · signal processing · future dependence · brain stimulation · phase estimation · conceptual replication

Admitted 1 citing publication

References

5
  1. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    The eligible readout pair tables and chronological source pulse indices come from this study through the direct parent package. They define the retained cohort. The present test does not select pairs by the earlier response agreement score.

  2. supportsAfter 20 ms blanking, future reflection changed symmetric 7 Hz phase more before pulses than controls in eight STReEF patients sci:sha256:a5d98494254b6ee0c428569159d9e483eb693318eee79f96f9c5e4176ca75f12

    This study found greater future dependence before pulses after short blanking in eight ds005448 patients. The present conceptual replication found the same direction in eight ds004696 sessions with a different filter, a 50 ms lead, and an initial repair that uses only the past. It also tests separate later intervals. It is not an exact repeat.

  3. usesReplacing data after pulses with zero changed theta phase labels 50 ms before pulses with a centered 1 s filter in eight SEEG sessions sci:sha256:17598dc78a0c15e696342a9b71328e9454995f0971df9ffd9f6f463a017449de

    This study supplied the lossless voltage epochs for eight SEEG sessions, the fixed readout and pulse selection, source hashes, the centered filter, and retrieval code. The new test adds a repair that uses only the past and separate later interval replacements. The no-repair reflection condition reproduced 1720 earlier trial values within their reported rounding.

  4. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analyzed voltage epochs and cohort derive from OpenNeuro ds004696 v1.0.1; the publication retains its source hashes and URLs.

  5. doi:10.1523/JNEUROSCI.2201-22.2023

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