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After 20 ms blanking, future reflection changed symmetric 7 Hz phase more before pulses than controls in eight STReEF patients

We tested whether future voltage changed a phase estimate before an electrical pulse. We used public SEEG data from eight STReEF patients, 96 conditions, and 960 pulses. The sample had 6,803 readout-condition rows. Each row was a remote bipolar pair in one condition. The filter was a symmetric complex Gaussian projection at 7 Hz. The estimate was 9.77 ms before each cut. A linear bridge replaced the first 20 ms after each cut. We then replaced future voltage with reflected earlier voltage. All pre-cut samples stayed fixed. The mean absolute phase change was 59.73 degrees at pulses and 56.04 degrees at control times. The paired difference was 3.69 degrees. Its 95 percent patient bootstrap interval was 2.85 to 4.54 degrees. All eight patient differences were positive. The exact two-sided patient sign-flip test gave p = 0.0078125. Control estimates also had large future dependence. The result measures sensitivity to one defined voltage replacement. It does not give error against true brain phase. It does not test an online device. The package has three figures, all phase products, 960 audit traces, checked source identities, code, and retrieval instructions.

phase estimation · temporal smearing · SEEG · electrical stimulation · future dependence · signal processing · brain-computer interface · patient bootstrap

Admitted 1 citing publication

References

7
  1. usesWith local time centering, equal windows raised mean early SEEG variance ratios from 0.46 to 1.01 in eight STReEF patients sci:sha256:af963a3e6cf35fc6ea31f827c54cd9e8b8ad9604155227bb41efff6898362020

    Uses the fixed sample, source metadata, pinned range identities, release proofs, and retained selection code. New phase products come from fresh raw ranges.

  2. usesA five-pulse check selected SEEG pairs with 60.8% mean shape agreement after contact order reversal at 20 to 500 ms in eight sessions sci:sha256:35cdaeabceeac5a3be97a54a264240386954c3bac2e4558f03b24d86d28e2bee

    Uses the original metadata-based sample selection and adjacent remote bipolar readout method. The selection code and license are retained.

  3. usesMean corrected SEEG change score was greater at 20 to 100 ms than at 100 to 500 ms after contact order reversal in eight people sci:sha256:2408c2a65355f6be8380bfa2f3d816dc2faf0e26b28992bab8fd5505960052a9

    Uses the eight-patient, 96-condition, 960-pulse sample and its pinned source range records through the direct parent. All range hashes matched.

  4. usesdoi:10.18112/openneuro.ds005448.v1.0.0

    Source dataset: STReEF ds005448 version 1.0.0; this study uses its SEEG voltage and metadata.

  5. supportsdoi:10.1016/j.ynirp.2025.100274

    Describes the source cohort and clinical stimulation protocol.

  6. doi:10.1016/j.neuron.2019.02.039
  7. doi:10.1007/s12021-022-09567-6

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