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Late SEEG variance exceeded pre-pulse variance after mean waveform removal in seven selected ds004696 patients

Late SEEG sample variance was higher after stimulation than before stimulation in all seven selected patients. The study used public OpenNeuro ds004696 version 1.0.1 data. It kept 80 stimulation groups and 1,516 contact-group rows, with ten pulses per group. The primary data had a 45 Hz low-pass filter. The time windows were 100 to 500 ms after each pulse and -450 to -50 ms before it. The analysis removed the time mean of each pulse and the mean waveform across pulses. The mean patient contrast was 2.19 dB, with a geometric variance ratio of 1.66. The 95 percent patient bootstrap interval was 1.40 to 3.24 dB. The exact two-sided patient sign flip test gave p = 0.015625 under independent patients and a symmetric zero-null contrast distribution. A template from separate pulses left a 2.04 dB increase after scalar fits. Nearby contact subtraction gave 2.05 dB in an exploratory check. These results describe variable corrected voltage. They do not identify its neural cause. The patient sample and source correction are fixed. The package preserves selected data, code, source records, results, checks, and source retrieval instructions.

SEEG · single-pulse stimulation · pulse-to-pulse variance · variance ratio · limbic system · epilepsy · intracranial electrophysiology

Admitted 7 citing publications

References

4
  1. usesFive pulses gave smaller 100–500 ms peak gaps than two pulses in seven limbic SEEG patients after fixed correction and 45 Hz filtering sci:sha256:1a90f67f4b64d631579af9d6d0f5ba2889176ab966fd947fa80e825719fa3389

    This study used the fixed off-stimulation-shaft voltage windows, source hashes, and retrieval records from this publication. It added the pulse variance and template residual analyses.

  2. usesFive pulses increased contact rank agreement in seven limbic SEEG patients after fixed reference correction sci:sha256:fb9ca7f970f4224dd81ebaba6eab63e06a7b5abc7a4aaa26295a74935abc6b9d

    This study kept the original group eligibility rules and first-ten-good-pulse selection from this publication. The preserved records give the initial selection and source procedures.

  3. doi:10.1523/JNEUROSCI.2201-22.2023
  4. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis used the selected SEEG data from OpenNeuro ds004696 version 1.0.1.

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