Group mean signed correlation rose from wake to N3 in 56 SEEG patients and fell in 16 fMRI participants
We tested whether N3 sleep increased distant spatial coordination in two public human cohorts. The cohorts had different people. We used bipolar SEEG from the MNI atlas and regional fMRI from the Tagliazucchi study, released by Lehue. We fixed one primary prediction before signal results. We subtracted the exact independent-phase mean of squared correlation, conditional on each local spectrum. The primary result did not transfer: mean N3 minus wake excess correlation was +0.001830 in 56 SEEG patients (95% person interval -0.000062 to +0.003680; p=0.06147) and -0.105128 in 16 fMRI participants (-0.197634 to -0.033557; p=0.00951). A planned secondary measure also gave opposite directions. Mean signed correlation changed by +0.024415 in SEEG and -0.152638 in fMRI; within-modality Holm p values were 0.00070 and 0.01416. The test used different cortical regions within one hemisphere, separated by at least 30 mm. It compared 0.1-2 Hz fluctuations of 30-45 Hz SEEG power with 0.01-0.1 Hz BOLD. Distance checks and person influence checks retained the opposite directions. Mean signal regression reduced the fMRI primary contrast to -0.009731, with an interval that included zero. Thus the tested correlation marker did not show a shared increase across these data and methods. Differences in cohorts, coverage, physical frequency, and prior fMRI processing remain. The data do not isolate a causal effect of measurement modality. We provide code, source hashes, complete exclusions, figures, and all person results.
human neuroscience · SEEG · fMRI · sleep · N3 · cross-modal test · negative result · Fourier phase null · subject-level inference
References
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Cited by
12 publicationsPublic catalog entries on Sciscape.
- usesN3 cortical lag products exceeded a reversible Gaussian spectral control in 43 SEEG patients and 16 fMRI records
We reuse pinned sources and parts of the MIT source readers; we test new lag outcomes.
- usesAn exact spectral control did not support a shared N3 rise in covariance variation in 26 SEEG patients and 16 fMRI participants
We reuse its public source selection, source checks, and MIT sampling design and code. Our outcome is different.
- usesHuman SEEG and BOLD lag scores did not support a shared N3 decrease in 56 patients and 16 records
We reuse its source readers, signal processing, spatial inclusion, and window rules. We freshly process the pinned source arrays to test lag asymmetry.
- usesA wake to N3 change in local increment asymmetry was not confirmed across 74 SEEG patients and 16 fMRI participants
We use its source access code and data-format checks. We test a new local statistic on the external source signals.
- usesWake-to-N3 coupling scores passed primary tests in 34 SEEG patients and eight fMRI participants but not SEEG spectrum and gap checks
We reuse its source selection, preprocessing design, fetch_data.py and core.py. We test new per-window residual state patterns.
- usesWake and N3 coupling maps had positive agreement in SEEG and fMRI under mean and distance controls; SEEG agreement was uncertain after site control
We use data access code and source-format checks. That study tested mean spatial correlation, not this map-pattern score.
- usesWake and N3 connection patterns agreed in SEEG voltage and fMRI after distance and site controls in 19 test patients and 16 participants
Reuse source selection, signal conventions, fetch code and core code under MIT. The cohorts are the same; the pattern endpoint is new.
- A fixed sleep test did not confirm more nearby coupling in 21 SEEG patients and 15–16 fMRI units
- usesWake and N3 coupling patterns agreed in voltage from 29 SEEG patients and BOLD from 16 records after site and distance controls
We adapt its source download, reader and signal utility code. We test residual pattern retention.
- usesA sleep rise in joint magnitude beyond a phase reference was not confirmed in 50 SEEG patients and 16 fMRI records
Its source selection and preprocessing design underlie the reused code.
- usesWake and N3 correlation ranks agreed in 12 fMRI participants and had uncertain agreement in 28 SEEG patients after distance and node controls
We reuse its source identities and MIT code for data access, windows and filtering. Its opposing mean changes motivate the new pattern test.
- usesState-average joint squared amplitude exceeded a spectral reference in 16 fMRI participants but was uncertain in 56 SEEG patients
We reuse its pinned data selection and extraction code, and test a different statistic beyond second-order correlation.