Four pulse groups give an unbiased fixed SEEG map score under stable means and independent errors
A compact stimulation map can use one waveform with a different amplitude at each site. A noisy fitted waveform can leave residual power even when that model is true. We give a score from four separate pulse groups that avoids a fitted direction. Its expected value is zero for a centered map of rank zero or one. The proof assumes stable response means and independent, mean-zero group errors. Correlated errors within a group are allowed. Algebra checks and 30,000 simulated maps test the method and its limits. We apply it to public OpenNeuro ds004457 version 1.0.2: five sessions, 183 sites, and 1,464 pulses. All five post-pulse scores exceed their matched pre-pulse scores. Fixed checks give the same ordering. These finite scores are descriptive and are not rank tests. Shared errors can give positive scores for a rank-one target. All 110 source files pass hash checks. A raw rebuild and a fresh numerical rerun pass exact comparisons. The package preserves proof, code, voltage bins, provenance, results, and four figures.
SEEG · electrical stimulation · response maps · rank estimation · unbiased estimator · independent errors · OpenNeuro
References
4- usesA fixed covariance rule gave higher SEEG site accuracy than a diagonal rule in offline tests from five patient sessions sci:sha256:1407cd9ac712a4bcd551a3738cc90c3fab309b871572cbd6fc644b41555f7886
This study uses the archived voltage bins, event and contact metadata, source manifest, raw extraction code, and site selection rules. It rebuilds all five selected sessions from the public raw source and checks the imported arrays.
- usesOne waveform learned from two pulses per site missed repeated site differences in five SEEG sessions sci:sha256:d08ca03b09b85e16bff0cce29a0e32d65988740ca9cc1eb935f43e2d66c2eadd
The earlier study shows that residual power outside a learned first waveform can be positive for a true rank-one map. This limitation sets the question for a four-group score that uses no fitted direction.
- usesdoi:10.18112/openneuro.ds004457.v1.0.2
The analysis uses selected data from OpenNeuro ds004457 version 1.0.2.
- doi:10.1523/JNEUROSCI.1325-22.2023
Cited by
4 publicationsPublic catalog entries on Sciscape.
- usesA four-group reciprocal shape contrast exceeded its pre-pulse control at 20 to 500 ms in seven SEEG sessions
Its four-group fixed-map score and proof informed the independent-repeat product argument. We adapt that principle to a two-direction determinant, with separate calibration weights and a pre-pulse control. We use no voltage data from that study.
- usesFirst and last pulse groups gave mixed SEEG energy changes from 20 to 100 ms at 134 sites in five sessions
Its independent-group proof informed the stable-mean and pulse-error assumptions and the shared-noise failure check. This study uses a simpler distinct-pulse energy identity and gives its own proof.
- usesResponses 1 and 4 gave 3.4% higher mean SEEG forecast error than responses 2 and 3 in five sessions at 20–500 ms
Uses the archived voltage bins, metadata, pinned source manifest, and extraction and selection code. All voltage inputs were rebuilt from the public raw files before this comparison.
- usesA 90% calibration voltage map left positive test contrast outside its space in five offline SEEG sessions
Its proof and shared-error examples informed the stable-mean and independent-error assumptions. Its four-group statistic differs from our fitted-subspace distance score.