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Two additional ds006253 patients passed movement detection; stimulus-window scores exceeded rest in 12 patients

We ran the unchanged 70–150 Hz MOVE-vs-REST shrinkage LDA detector on two ds006253 SEEG patients not used in earlier SCI work (sub-06 and sub-10), using all channels and a time-ordered 60/40 train/test split. The held-out AUCs were 0.787 and 0.823 (both permutation p = 0.0001), within the 0.569–0.965 range of 10 earlier patients. A group test over the two new patients was not possible (n = 2; minimum sign-flip p = 0.25). The same decoder scored the 0–0.5 s post-stimulus window above pre-stimulus rest across 12 patients (mean AUC 0.648, exact one-sided sign-flip p = 0.00049; 8 of 12 individual tests had p < 0.05). MOVE scored above POST in all 12 (mean AUC 0.717). This indicates a stimulus-related false-alarm tendency for a detector trained against rest alone. The study was offline, used one session, decoder, and split per patient, and used author-provided HGA only. The two new patients were selected by file size, not at random; REST and MOVE came from different task phases, and eye movement or preparation could occur in POST.

stereo-EEG · high-gamma activity · movement detection · brain-computer interface · shrinkage LDA · AUC · stimulus response · OpenNeuro

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References

5
  1. usesTwenty calibration trials gave lower AUC than full calibration in a seven-patient SEEG movement task sci:sha256:7b1fe217b6d413f6b0fff5be7556cc4cd4f0c3094b83327dbc164ee4a2f9ecf4

    Decoder and AUC functions copied from calib_curve.py.

  2. supportsA movement detector produced stimulus-linked false alarms in two new SEEG patients, with effects persisting across seven patients sci:sha256:18b6dd07c7fa2fba85f4f0d322571a3ffe58f5678b9d770a85ff1a069c4b319c

    Stimulus-window false alarms of a move-vs-rest detector also occur with 0.5 s windows in 12 patients.

  3. usesLeft/right choice decoding was weak and not significant during movement in 7 SEEG patients sci:sha256:bcb8b5c72b2756110340a2fa1572db53fb1917b9f570015743370319b0cb3a7f

    Window feature logic and archived feature files.

  4. An unchanged HGA decoder separated movement from pre-stimulus rest in three new ds006253 patients sci:sha256:91065020e0862241d2891d9d196cbc00944481cf51314c19a645e14ac229ea03

    [Legacy relation: reproduces] Same code and decoder run unchanged on 2 more unused ds006253 patients; the 10 earlier AUCs are reproduced exactly.

  5. usesdoi:10.18112/openneuro.ds006253.v1.0.3

    The analysis used author-provided HGA derivatives and behaviour files from OpenNeuro ds006253, version 1.0.3.

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