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A temporal interaction test did not show a shared violation in eight ECoG patients and six fMRI adults

We tested whether interactions between pairs of time blocks explain visual response areas in two separate human studies. We derived an exact contrast from five visual patterns and a blank. It needs no fitted kernel or time constant. Under stationary pair interactions and a complete stable area readout, the contrast is zero. Public data supplied 98 selected ECoG contacts from eight epilepsy patients and eight fMRI records from six adults. The fixed test did not show a shared violation. The ECoG mean contrast was -0.472 single-duration RMS units (95% person bootstrap interval -1.552 to +0.705; two-sided sign-flip p=0.421875). The original fMRI mean ranged from -0.729 to +0.088 across 72 possible repeated-record links, with largest p=1. A later correction used the measured fMRI blank. Its mean ranged from -1.401 to -0.659, but its largest p was 0.40625 and its interval union included zero. ECoG pre-stimulus subtraction changed its mean sign. The corrected analysis followed outcome inspection. These results do not establish a shared neural effect or absent higher-order interactions. We provide a scope proof, counterexamples, and a trial-allocation rule that lowers theoretical variance by 38.64% under equal-noise and independent-trial assumptions. Clinical sampling, source selection, baseline choices, finite tails, timing and vascular effects limit interpretation. The package preserves code, source versions and terms, compact inputs, plans, the correction history, all results, figures and repeat instructions.

ECoG · fMRI · visual adaptation · temporal interaction · Volterra models · reproducible reanalysis

Admitted 7 citing publications

References

8
  1. usesFixed recovery tests did not show a shared model violation in eight ECoG patients and six fMRI adults sci:sha256:a897f45ddd7b7f39f0ff91676d8367575836148c09a055ef11f9bd6f4a39f49e

    We reuse its verified trial scalars, source code, original fMRI file, and provenance. We retain its run-start correction.

  2. usesSingle-image fits of a simple temporal model did not confirm a shared repetition prediction gain in 8 ECoG patients and 6 fMRI adults sci:sha256:b15151390f0a4a1de598679f3596a0fed817c6827c52d261e29e060f598ecb9b

    Its failed temporal prediction test and source limitations helped define this model-class question.

  3. usesA test of adaptation mixtures that start at zero did not show shared violations in five ECoG patients and six fMRI adults sci:sha256:dedc52d746aea6c692de709a090b576beaebb9a4b3777be333d1f3d4180306b5

    Its positive adaptation-mixture test motivated a different exact test for signed pair interactions.

  4. usesdoi:10.18112/openneuro.ds004194.v3.0.0

    This version supplies the human ECoG source epochs and metadata behind the reused compact data.

  5. usesdoi:10.1523/JNEUROSCI.1812-21.2022

    This source study describes the ECoG task and processing.

  6. usesdoi:10.1523/JNEUROSCI.1724-17.2017

    We reanalyze its human fMRI data from OSF v843t, file wn2q9, version 1.

  7. doi:10.1371/journal.pcbi.1007484

    This prior work models visual temporal responses with delayed gain control.

  8. doi:10.1016/j.mbs.2009.11.010

    This prior work describes quadratic system identification in the paired-pulse paradigm.

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