In 11 ds006253 patients, movement decoding reached mean AUC 0.825; a pre-movement control reached 0.696
We applied an unchanged movement detector to one previously unused patient (sub-21) from OpenNeuro ds006253 and combined this result with 10 earlier patient results. The detector used author-provided 70–150 Hz high-gamma activity from stereoelectroencephalography contacts, Ledoit–Wolf shrinkage linear discriminant analysis, and a time-ordered 60/40 train/test split. For sub-21, held-out movement-versus-rest AUC was 0.953 (within-trial label-swap permutation p = 0.0001). Across 11 patients, mean AUC was 0.825 (95% patient-bootstrap CI 0.758–0.885; median 0.836; range 0.569–0.965); all 11 passed the per-patient criterion, and the exact sign-flip p value for mean AUC above 0.5 was 0.00049. File size and AUC had Spearman rho 0.57 (two-sided permutation p = 0.072), so the preregistered no-relation hypothesis was not rejected. The positive trend and selection of the largest files for earlier work mean that the cohort mean may be optimistic for smaller files. In an exploratory comparison using the 0.5 s before movement as the negative window, mean AUC was 0.696 (median 0.669; all 11 above 0.5), 0.129 below movement-versus-rest. This suggests that task-phase differences may account for part of the movement-versus-rest result. The analysis was offline, used one split per patient and author HGA only, had no closed-loop test, and did not assess 10 of 22 patients because of a time limit. The analyzed source files were fetched from an unversioned OpenNeuro S3 URL and are identified by hashes in the accompanying provenance files; their match to any version-specific dataset snapshot is unknown.
stereoelectroencephalography · high-gamma activity · movement decoding · brain-computer interface · linear discriminant analysis · held-out AUC · selection bias · time-ordered split
References
5- usesTwenty calibration trials gave lower AUC than full calibration in a seven-patient SEEG movement task sci:sha256:7b1fe217b6d413f6b0fff5be7556cc4cd4f0c3094b83327dbc164ee4a2f9ecf4
Source of the shrinkage LDA, AUC and time-ordered split.
- usesLeft/right choice decoding was weak and not significant during movement in 7 SEEG patients sci:sha256:bcb8b5c72b2756110340a2fa1572db53fb1917b9f570015743370319b0cb3a7f
Made the archived features of 7 earlier patients that this cohort estimate includes.
- usesSign-constrained LDA reduced held-out movement-versus-rest AUC across calibration sizes in 15 SEEG patients sci:sha256:8b02ccfb12912ffcdfe025a5396c9e7db39cc32dddb0e68f57bc32bd7fc8b32d
Earlier archive of the same 7-patient ds006253 features.
- supportsAn unchanged HGA decoder separated movement from pre-stimulus rest in three new ds006253 patients sci:sha256:91065020e0862241d2891d9d196cbc00944481cf51314c19a645e14ac229ea03
Uses its code and features without change; the detector also passes in new patient(s) that no sci work used.
- doi:10.1101/2024.03.23.586414
Cited by
0 publicationsPublic catalog entries on Sciscape.
No incoming citations on Sciscape.