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Energy center times met a 10 ms repeatability target less often than peak times in eight limbic SEEG sessions with a 20–500 ms window and a shape check on the first five pulses

We compared two response time summaries in public stereoelectroencephalography (SEEG) data from eight patients. The data were from OpenNeuro ds004696, version 1.0.1. A correlation check between means of the first two and next three pulses selected 196 of 886 stimulation-site and readout pairs. We used a 20–500 ms window. We compared the first five and final five good pulses. The energy center used time weighted by squared centered voltage. The peak used the largest absolute centered voltage. The planned mean-change difference was 0.92 ms, with a descriptive 95% patient bootstrap interval of [-8.88, 9.33] ms. This result did not show a mean-change advantage for the energy center. The 10 ms target was met by 34.3% of energy centers and 77.0% of peaks, with equal patient weight. The energy center fraction was lower in every patient. Shorter windows gave different results. We derived and checked a finite-grid timing bound. We also saved trial products for a noise audit. The study reuses a known cohort and is exploratory. It tests time-summary repeatability within sessions. It does not test neural delay or live BCI control.

stereoelectroencephalography · SEEG · limbic stimulation · response timing · energy center · dominant peak · repeatability · brain-computer interface · finite-grid bound · trial noise

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References

5
  1. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    We adapted the source extractor and its contact and reference checks. We rebuilt all eight source files and added individual-trial product summaries.

  2. usesAn early timing check selected SEEG pairs with higher mean 10 ms peak precision in a 20–500 ms window in eight patient sessions sci:sha256:110cef22b824b0ef3606807e1eb505735ba0309f2b9d1e676d77412b1f279117

    We used the exact mean waveforms and cohort records. We compared new energy center scores with peak scores on the same readouts. This is a new analysis of the same cohort.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    This study uses processed voltage traces from OpenNeuro ds004696 version 1.0.1.

  4. doi:10.1523/JNEUROSCI.2201-22.2023
  5. supportsdoi:10.1371/journal.pcbi.1011105

    This paper describes canonical response parameterization used to obtain the source response traces; the present analysis uses the processed traces and not the fitted response.

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