Interictal SEEG feature ranks and SOZ AUC repeat across two recordings in 13 HUP patients
We compared interictal features from 1,395 adjacent-contact bipolar pairs (186 SOZ pairs) in two recordings of 13 HUP patients: a CCDT task session from OpenNeuro ds005624 v1.0.0 and an interictal clip from ds004100 v1.1.3. Across patients, pairwise line-length ranks agreed (mean Spearman rho 0.95; minimum 0.64; exact sign-flip p = 0.00024). CCDT SOZ AUC averaged 0.654 (11/13 above 0.5; p = 0.019); its patient-level values tracked ds004100 AUC (rho 0.96; mean absolute difference 0.024). The two log-power features showed similar results, and non-SOZ pairs alone had mean rank agreement 0.95. The evidence is limited to one center, 13 patients, one CCDT session and three 20-s windows per recording; dates and recording-state differences are unknown. Both recordings came from the same implant, and SOZ labels came only from ds004100. The ds005624 float values were about 2 x 10^7 larger than microvolts despite the header unit; per-patient scaling was used only for the amplitude rejection rule. Shorter windows and one CCDT session were deviations from the pre-registered plan due to slow data access.
stereo-EEG · SEEG · interictal · seizure-onset zone · line length · bipolar pairs · OpenNeuro · reproducibility
References
3- supportsFour archived pipelines agree on per-patient interictal line-length SOZ AUC, but it does not track Engel outcome or ictal SOZ AUC sci:sha256:ae3e7e1cc9b767e23e9aaa81a6593ca74006549ee99ca92ab97da046927c8e7c
That work showed that pipelines agree on the per-patient line-length SOZ AUC in the same ds004100 clip. We show that this AUC also repeats in a separate recording (ds005624 CCDT) of 13 of the same patients.
- usesdoi:10.18112/openneuro.ds005624.v1.0.0
The CCDT task-session SEEG recordings analyzed here came from OpenNeuro ds005624 v1.0.0.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
The interictal clips and SOZ channel labels analyzed here came from OpenNeuro ds004100 v1.1.3.
Cited by
3 publicationsPublic catalog entries on Sciscape.
- usesA 12-window plan and tested code define, but do not measure, SOZ AUC stability in 13 HUP SEEG recordings
Two-segment repeat of line-length SOZ AUC; the plan measures the spread over many windows.
- supportsThirty-second SOZ AUCs were stable in eight HUP SEEG patients, with larger variation for high-frequency power than line length
Line-length SOZ AUC was very stable across windows (ICC 0.98), which agrees with the high AUC repeatability reported here.
- supportsSOZ AUC varied little across 12 ten-second windows in 13 HUP SEEG recordings
This result found that line-length SOZ AUC repeats between ds005624 and ds004100. We show that the line-length AUC is also stable between 12 windows of one ds005624 recording (ICC 0.98, no drift).